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The daughters of mothers who menstruated early, themselves menstruate early. Animals fed upon thyroid during pregnancy, comparable to the thyrocentric, give birth to offspring with a very large thymus, comparable to the thymocentric. Women with partial thyroid deficiency, or myxedema, bear cretins.

The thyrocentric is predisposed to heart disease, as well as intestinal disturbances. The pituitocentric is liable to periodic and cyclic upsets in his health. Narcotism, the craving for narcotic or stimulant drugs, and its subvariety, alcoholism, has been found most often among the thymocentrics.

The types of personality sketched the thyrocentric, the pituitocentric, the adrenocentric, the thymocentric, the gonadocentric are really prototypes, the great kingdoms of personality, to which individuals can be assigned, by hall marks which facilitate their classification. They may also be described as the pure endocrine types, which include a minority of a population.

All kinds of questions arise as soon as one attempts to consider the bearing of this underlying principle upon concrete situations. What happens, say, when a pituitocentric mates with a thyrocentric? Or when a pituitocentric marries a pituitocentric? Is there a reinforcement or a cancellation of the dominant endocrine?