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Updated: May 13, 2025


A species of thistle was once believed to have the curious virtue of driving away melancholy, and was hence termed the "melancholy thistle." According to Dioscorides, "the root borne about one doth expel melancholy and remove all diseases connected therewith," but it was to be taken in wine.

Other important Byzantine writers were Aetius and Alexander of Tralles, both of whom were strongly under the influence of Galen and Hippocrates. Their materia medica was based largely upon Dioscorides. From Byzantium we have the earliest known complete medical manuscript, dating from the fifth century a work of Dioscorides one of the most beautiful in existence.

He seems also to have exercised some of the functions of Prime Minister to the Caliph, and took advantage of diplomatic relations between his sovereign and the Byzantine Emperor to obtain some works of Dioscorides. These he translated into Arabian with the help of a Greek monk, whom he seems also to have secured through the diplomatic relations.

Some of Galen's works are mere drug lists, little superior to those of Dioscorides; with the depression of the intelligence that corresponded with the break up of the Roman Empire, it was these that were chiefly seized on and distributed in the West.

The frequency with which fragments of him are encountered in papyri shows how popular his work was in Egypt in the third and fourth centuries. One of the earliest datable Greek codices in existence is a glorious volume of Dioscorides written in capitals, thought worthy to form a wedding gift for a lady who was the daughter of one Roman emperor and the betrothed of a second.

After Celsus comes Dioscorides in the first century A. D. He was a Greek military surgeon of Cilician origin who served under Nero, and in him the Greek intellect is obviously beginning to flag. His work is prodigiously important for the history of botany, yet so far as rational medicine is concerned he is almost negligible.

The actual printing of collected editions of Hippocrates and Galen came rather late, for the debased taste of the Renaissance physicians continued to prefer Dioscorides and the Arabs, of whom numerous editions appeared, so that medicine made no advance corresponding to the progress of scholarship.

The curative goddess rode between the four eminent physicians, Hippocrates, Galen, Dioscorides, and Theophrastus, and was attended by two footmen and four pike-bearers. Last of the allegorical personages came Minerva, prancing in complete steel, with lance in rest, and bearing her Medusa shield.

And because he studied the science of herbs in Dioscorides, being much inclined thereunto by nature, and delighting to understand the property and virtue of each one of them, at last he abandoned painting and gave himself to the distilling of simples and to seeking them out with all diligence. Changing thus from painter to physician, for a long time he followed this art.

The curative goddess rode between the four eminent physicians, Hippocrates, Galen, Dioscorides, and Theophrastus, and was attended by two footmen and four pike-bearers. Last of the allegorical personages came Minerva, prancing in complete steel, with lance in rest, and bearing her Medusa shield.

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