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Updated: May 11, 2025
The significance of this affinity of the brain for adrenalin begins to be seen when I call attention to the following striking facts: 1. Adrenalin alone causes hyperchromatism followed by chromatolysis, and in overdosage causes the destruction of some brain-cells.
Histologic Changes in the Brain-cells in Relation to the Maintenance of Consciousness and to the Production of the Emotions, Muscular Activity, and Fever
Dante's "Inferno," Canto XXIV, lines 89, 90. all the stimuli reached the brain-cells simultaneously, the cells would find themselves in equilibrium and no motor act would be performed.
If you cannot sit in your gold and white boudoir, and be true to Ernest while he battles a few more years with destiny, then you could not remain loyal in thought while you held your numb fingers over a chilly radiator in an uncomfortable flat, or omitted dessert from your dinner menu to cut down expenses. Your brain-cells have been developed in opulence.
In the past we have had one set of men do all the work, and another set had all the culture: one hoes and another thirsts. There are whole areas of brain-cells which are evolved only through the efforts of hand and eye, for it is the mind at last that directs all our energies. The development of brain and body go together manual work is brain-work.
If nitrous oxid anesthesia and sleep are chemically identical, then we have a further clue to one of the primary mechanisms of life itself; and as a practical corollary one might be able to produce artificial sleep which would closely resemble normal sleep, but which would have this advantage, that by using an anesthetic which interferes with oxidation the brain-cells might be reconstructed after physical fatigue, after emotional strain, or after the depression of disease.
Such an animal is known as a "spinal dog." Now, in this animal, the abdomen and hind extremities had no direct nerve connection with the brain. We must conclude, therefore, either that nitrous oxid protects the brain-cells against trauma or that ether predisposes the brain-cells to exhaustion as a result of trauma.
Their brain-cells at birth offered so little resistance to the evil occult influences that they received, in full, all the lower germs of thought inoculated by the occult brains. Drink, gluttony, cruelty, all came to their infant cerebrums cotemporaneously.
It is possible now to measure only the evidences of the effects on the brain-cells of gross and violent mental activity. At some future time it will doubtless be possible so to refine the technic of brain-cell examinations that more subtle changes may be measured.
Anoci. * not to venture too far in serious cases. If we believe that, in accordance with the law of phylogenetic association, a continuous stimulation of both the brain and the thyroid gland, accelerated by summation, plays a role in the establishment of the pathologic interaction seen in Graves' disease, then it is but the next step to assume that if the nerve connection between the brain and the thyroid be severed, or if the lobe be excised and the patient reinforced by a sojourn in a sanatorium or in some environment free from former noci-associations, he may be restored to normal health, provided that the brain-cells, the heart, or other essential organs have not suffered irreparable damage.
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