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I should expect to see it appear under forms of great simplicity, endowed, like existing fungi, with the power of determining the formation of new protoplasm from such matters as ammonium carbonates, oxalates and tartrates, alkaline and earthy phosphates, and water, without the aid of light.

It should be noted, however, that very few of these organic compounds react quantitatively with the permanganate, as is the case with oxalic acid and the oxalates.

However, we must not lose sight of the fact that these crystals may be simply an accompaniment of the too frequent emissions, and that the presence of oxalates in the urine may be caused by some disturbance in the nutritive processes that go on in the body, which disturbance causes not only the irritability of the sexual apparatus, but also the presence of the crystals.

Another cause of too frequent nocturnal emissions and one wholly separate from any abuse of the sexual function is irritability and mechanical irritation of the sexual apparatus perhaps especially the membranous and prostatic portion of the urethra caused by the presence of an excessive amount of oxalates in the urine.

Intestines slightly inflamed, stomach sometimes quite healthy. Treatment. Warm water, then chalk, carbonate of magnesium, or lime-water, freely. Not alkalies, as the oxalates of the alkalies are soluble and poisonous. Castor-oil. Emetics, but not stomach-pump. Fatal Dose. One drachm is the smallest, but half an ounce is usually fatal. Method of Extraction from the Stomach.

Oxalates occur in the urine in sharp angular crystals and would seem to be in a high degree irritating to the tender mucous membrane of the upper part of the urethra. The almost invariable presence of these crystals in excess in those cases that have not been accounted for by abuse of the sexual function leads one to adopt the plausible theory that the crystals are the cause of the irritability.

The leading symptom is tetanic spasm. 5. =Poisons Affecting the Heart.= These kill by sudden shock, syncope, or collapse. They comprise prussic acid, dilute solution of oxalic acid and oxalates, aconite, digitalis, strophanthus, convallaria, and tobacco. 6. =Poisons Acting on the Lungs.= These have for their type carbonic acid gas and coal gas.

Apoplexy may also be caused by other acids and drug poisons which soften, corrode and destroy the walls of the blood vessels in the brain. In individuals of different constitutions, accumulations of uric acid, xanthines, oxalates of calcium and various other earthy substances form stones, gravel or sandy deposits in the kidneys, the gall bladder and in other parts and organs.

Hydrochloric acid has the advantage of forming soluble compounds with the alkaline earths, but its solutions cannot be boiled without danger of loss of strength; sulphuric acid solutions may be boiled without loss, but the acid forms insoluble sulphates with three of the alkaline earths; oxalic acid can be accurately weighed for the preparation of solutions, and its solutions may be boiled without loss, but it forms insoluble oxalates with three of the alkaline earths and cannot be used with certain of the indicators.

If acids, xanthines and oxalates of lime form earthy deposits along the walls of arteries and veins, these vessels harden and become inelastic, and their diameter is diminished. This obstructs the free circulation of the blood and causes malnutrition of the brain and other vital organs. Furthermore, the blood vessels become brittle and break easily and there is danger of hemorrhages.