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Updated: June 25, 2025


On the other hand, imagine the prospects for infection when the child is born through a birth-canal filled with mucous patches or with a chancre on the neck of the womb. Children infected in this way at birth do not develop the true hereditary form of the disease, but get the acquired form with a chancre and secondary period, just as in later life.

In consequence of their divergence from the typical chancre, and of their being often met with in persons who, from age, surroundings, or moral character, are unlikely subjects of venereal disease, the true nature of erratic chancres is often overlooked until the persistence of the lesion, its want of resemblance to anything else, or the onset of constitutional symptoms, determines the diagnosis of syphilis.

Syphilis which starts from a chancre elsewhere than on the genitals runs the same course and may conceal itself quite as effectively as syphilis from the usual sources, and for that reason may even more easily escape notice because misinterpreted at the start.

The patient with a beginning chancre, at the advice of a drug clerk, tries a little calomel powder on the sore, and it either "dries up" and secondary symptoms of syphilis appear in due course, or it gets worse or remains unchanged and the patient finally goes to a doctor or a dispensary to find that his meddling has lost him the golden opportunity of aborting the disease.

#The Soft Sore, Soft Chancre, or Chancroid.# The differential diagnosis of syphilis necessitates the consideration of the soft sore, soft chancre, or chancroid, which is also a common form of venereal disease, and is due to infection with a virulent pus-forming bacillus, first described by Ducrey in 1889. Ducrey's bacillus occurs in the form of minute oval rods measuring about 1.5

The primary stage was supposed to extend from the appearance of the first sore or chancre to the time when an eruption appeared over the whole body. Since the discovery of the Spirochæta pallida, the germ of the disease, our knowledge of what the germ does in the body, where it goes, and what influence it has upon the infected individual, has rapidly extended.

A patient seeking advice should go to his doctor at once, and absolutely untreated. Then, again, irritating treatment applied unwisely to even a harmless sore may make a mere chafe look like a hard chancre, and result in the patient's being treated for months or longer for syphilis.

Syphilitic affections of the nails assume various aspects. A primary chancre at the edge of the nail may be mistaken for a whitlow, especially if it is attended with much pain. Other forms of onychia occur during secondary syphilis simultaneously with the skin eruptions, and may prove obstinate and lead to shedding of the nails. They also occur in inherited syphilis. In addition to general treatment, an ointment containing 5

A chancre within the orifice of the urethra is rare, and, being concealed from view, it can only be recognised by the discharge from the meatus and by the induration felt between the finger and thumb on palpating the urethra.

In 1879 a new stage of more precise knowledge of the venereal diseases began with Neisser's discovery of the gonococcus which is the specific cause of gonorrhoea. This was followed a few years later by the discovery by Ducrey and Unna of the bacillus of soft chancre, the least important of the venereal diseases because exclusively local in its effects.

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