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Updated: July 20, 2025
For the same reason, and that the blood may not regurgitate upon the pulmonary veins, and thus the force of the ventricle in propelling the blood through the system at large come to be neutralized, it is that these mitral valves excel those of the right ventricle in size and strength and exactness of closing.
Before the heart muscle actually weakens, the blood pressure has been increased more or less constantly, perhaps permanently, until such time as the left ventricle fails. The left ventricle from tobacco alone, without any other assignable cause, may become dilated and the mitral valve become insufficient.
His explanations were practically the same as those given to-day first the contraction of the auricle, sending blood into the ventricle; then ventricular contraction, making the pulse, and sending the blood into the arteries. He had thus demonstrated what had not been generally accepted before, that the heart was an organ for the propulsion of blood.
Furthermore, he demonstrated that the cavities of the left side of the heart what we now call the left auricle and the left ventricle are, like the arteries, full of blood during life, and that that blood was of the scarlet kind arterialised, or as he called it "pneumatised," blood.
Buck mentions a case of hydatid cysts in the wall of the left ventricle, with rupture of the cysts and sudden death. It is surprising the extent of injury to the pericardium Nature will tolerate. In his "Comment on the Aphorisms of Hippocrates," Cardanus says that he witnessed the excision of a portion of the pericardium with the subsequent cure of the patient.
For I had no hopes to see any of your servants, or to hear from you, before I had finished our voyage; and contented myself with the dear remembrance of your august majesty, deeply impressed in the hindmost ventricle of my brain, often representing you to my mind.
In man they are more numerous in the left than in the right ventricle, more abundant in the ventricles than in the auricles; and occasionally there appear to be none present in the auricles. They are numerous in the large, more muscular and hardier bodies of countrymen, but fewer in more slender frames and in females.
At this stage the heart, which has already shown some trouble, becomes unable to force the blood properly against this enormous resistance of inelastic vessels and the blood pressure begins to fail as the left ventricle weakens. Edema, failing heart, perhaps aneurysms, peripheral obstruction, or hemorrhages are the final conditions in this chronic disease of arteriosclerosis.
The heart, therefore, ceases to pulsate sooner than the auricles, so that the auricles have been said to outlive it, the left ventricle ceasing to pulsate first of all; then its auricle, next the right ventricle; and, finally, all the other parts being at rest and dead, as Galen long since observed, the right auricle still continues to beat; life, therefore, appears to linger longest in the right auricle.
If the left ventricle becomes dilated the mitral valve may become insufficient, when the usual lung symptoms occur, with hypertrophy of the right ventricle; and if it fails, the usual venous symptoms of loss of compensation follow. This lesion not infrequently causes epistaxis, hemoptysis and hematemesis. Digitalis is always of value in these cases, but it should not be pushed.
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