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Updated: June 8, 2025


The animals so treated became immune; that is, exempt from the infection of the given disease. Pasteur gave public demonstrations in the fields near Paris, using the disease called splenic fever, and sheep as the subjects of his experimentation. The whole civilized world was astonished with the results. The tests were conducted in such a way as to preclude the possibility of error.

A greater discovery was already at the door. Dr. Koch began a careful investigation into the nature of consumption. His discovery of the germ of splenic fever, and that of chicken cholera, as well as the general results in this direction in other laboratories of Europe, led him to the conjecture that consumption also is a zymotic or bacterial disease.

Further, just as the discovery of the cause of scabies proved the absurdity of many of the old prescriptions for the prevention and treatment of that disease; so the discovery of the cause of splenic fever, and other such maladies, has given a new direction to prophylactic and curative measures against the worst scourges of humanity.

The blood is then pumped into general and systemic circulation, where it reaches all parts of the body, delivering nutrition and oxygen at a cellular level. On its return flow, a large proportion of the depleted blood is collected by the gastric, splenic and superior and inferior mesenteric veins that converge to form the large portal vein which enters the liver.

In particular they led the French physician Devaine to return to some interrupted studies which he had made ten years before in reference to the animal disease called anthrax, or splenic fever, a disease that cost the farmers of Europe millions of francs annually through loss of sheep and cattle.

According to the review of this article, Toldt explains the case by assuming that other parts of the celomic epithelium, besides that of the mesogastrium, are capable of forming splenic tissue. Jameson reports a case of double spleen and kidneys.

At the present time, science, working in the light of clear knowledge, has attacked splenic fever and has beaten it; it is attacking hydrophobia with no mean promise of success; sooner or later it will deal, in the same way, with diphtheria, typhoid and scarlet fever.

In animals it is characterised by symptoms of acute general poisoning, and, from the fact that it produces a marked enlargement of the spleen, is known in veterinary surgery as "splenic fever."

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