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Updated: May 12, 2025


As indican in the urine gives evidence of putrefactive changes in the intestines and the probability of the absorption of toxins from the intestines, although we have no real proof that these toxins are the direct cause of hypertension, our patient is undoubtedly physically better, and will have less arterial tension when this intestinal condition is removed.

The prostrating effect on the muscular system of the septic or putrefactive poison was nothing to be compared to the paralyzing effect of opium.

There is a small percentage of people who are not quite so irritable as others; in these the contraction, constriction or fixation the embargo laid on these parts by nature in her conservative effort at preventing movement is not established quite so early, and the efforts on the part of doctors to force a movement are more successful in cleaning out a part of the accumulation; or there may come a diarrhea from the putrefactive poisoning which is causing the infection of the cecum or appendix and leading to abscess, and this causes a partial cleaning out before fixation is established; in these cases there is never so much vomiting nor nausea, neither do they suffer so much pain for there is not the usual accumulation in the alimentary canal to excite the peristaltic movement.

Usually they are irregular, nodularly thickened or indurated; sometimes they are raised and crater-like. The floor of the ulcer is smooth and glazed, or occupied by necrosed tissue, and the discharge is watery and blood-stained, and as a result of putrefactive changes may become offensive.

"It was noticed that while the raw sewage filters very slowly, so that 500 c.c. required 96 hours to pass through a paper filter, the electrically treated sewage settled well and filtered rapidly. "Samples of the raw sewage, having but little smell when fresh, stank strongly on the third day. The treated samples, however, had no smell originally, and remain sweet, without putrefactive change.

You know the indols, the phenols, and the amins are produced both by putrefactive bacteria and by the process of metabolism, the burning up of the tissues in the process of utilizing the energy that means life. But under normal circumstances, the amins are not present in the blood in any such quantities as I have discovered by this new method of diffusion."

Living micro-organisms have never been detected in breezes coming from the sea, but in those blowing out from the shore large numbers may be found. In water tainted with organic matter putrefactive bacteria will flourish, whereas pure water is fatal to their existence.

These are the Monads, they are strictly putrefactive organisms, they are midway in size between the least and largest Bacteria, and are, from their form and other conditions, more amenable to research, and twelve years ago I resolved, with the highest power lenses and considerable practice in their use, to attack the problem of their origin; whether as physical products of the not-living, or as the natural progeny of parents.

The muscles then become pulpy, and assume a dark greenish colour, the whole body at length becoming changed into a soft, semi-fluid mass. The organ first showing the putrefactive change is the trachea; that which resists putrefaction longest is the uterus. Bodies which remain in water putrefy more slowly than those in air.

That he was exposed to the matter when it had undergone the putrefactive change is highly probable from the doctor's observing that the sick cows at the farm gave out an OFFENSIVE STENCH FROM THEIR UDDERS. However, I must remark that it is unusual for cattle to suffer to such an extent, when disordered with the cowpox, as to make a bystander sensible of any ill smell.

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