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Updated: June 11, 2025
If the blood pressure is low, or not higher than is best for the patient, such treatment would be inadvisable. If, from the supposed cause, iodid seems to be indicated, it should be given in small doses and continued for some time. It is often wise, however, to give small doses, as 0.10 or 0.20 gm. Iodid tends to prevent the progress of connective tissue formation.
As soon as all acute symptoms have ceased, rheumatic or otherwise, and the temperature is normal, the amount of food should be increased; the strongly acting drugs should be stopped; the alkalies, especially, should not be given too long, and the salicylates should be given only intermittently, if at all; iron should be continued, massage should be started, and iodid should be administered, best in the form of the sodium iodid, from 0.1 to 0.2 gm.
It should not be used, except if specially indicated, in broken compensation or in other myocardial weakness. Iodids: These have no immediate action. The vasorelaxation that often occurs from iodid is quite likely due to the stimulation of the thyroid gland by the iodin, and the thyroid gland secretes a vasodilating substance.
In such cases the iodid should be stopped immediately, of course, and the proper treatment begun. Under this head it is not proposed to consider disturbances of the heart due to infections, to cardiac disease, or to localized or general acute or chronic disease, but to discuss disturbances due to the absorption of irritants froth the intestines, and to alcohol, tobacco and caffein.
A very practical and fairly successful method of treatment consists in the aspiration of a quantity of synovia and injecting tincture of iodin. Cadiot recommends the drainage of synovia with a suitable trocar and cannula and injecting a mixture consisting of tincture of iodin, one part, to two parts of sterile water, to which is added a small quantity of potassium iodid.
Alcohol may be of benefit. If syphilis is a cause of the condition, iodids are always valuable. If syphilis is not a cause and arteriosclerosis is present, small doses of iodid given for a long period are beneficial, although it may not much reduce the blood pressure or decrease the plasticity of the blood. Iodid is a stimulant to the thyroid gland, and therefore it is on this account valuable.
Patients under iodid need not be seen so frequently; those under nitroglycerin or alkalies still less frequently. But all patients under the active management of hypertension should be seen at from one to three week intervals, and the urine should be repeatedly examined and the blood pressure carefully recorded.
If he does not sleep well, there is no hypnotic drug so valuable in his case as chloral. This should not be long given, but it will produce the purest kind of sleep and lowers the blood pressure. If any other drug is needed, nitroglycerin is the best. If arteriosclerosis is present, sodium iodid in small doses, 3 grains two or three times a day, is valuable.
If the indications for an iodid are present, such as sclerosis anywhere, or unabsorbed inflammatory products, exudation in or around the heart, or an apparent insufficiency of the thyroid, from 0.1 to 0.2 gm. It is sometimes a question whether small doses of iodid are not actually stimulant to the heart, possibly through the action on the thyroid gland.
Deficiency in the thyroid secretion will always cause a heart to be slower than normal. The more marked and serious the hypothyroidism, the slower the heart is apt to be. When such a condition is diagnosed, the treatment is thyroid extract; or if the insufficiency is not great, small doses of an iodid should be given.
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