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It commences as a diffuse haziness or steaminess near the centre of the cornea, and as it spreads the entire cornea assumes the appearance of ground glass. The chief complaint is of dimness of sight, which may almost amount to blindness, but there is little pain or photophobia; a certain amount of conjunctival and ciliary congestion is usually present, and there may be iritis in addition.

Upon examination of the lid, no opening could be made out where the sting had penetrated, and a minute inspection of the conjunctival surface with a good glass failed to reveal any foreign substance. Cleansing the lid thoroughly, and carefully inspecting with a lens under strong light, a minute dark point was made out about the center of the lid.

The conjunctival flap thus formed is turned back over the cornea, and the fragment of sclera that is left attached to the cornea is removed by means of a fine pair of delicate curved scissors. Following this an iridectomy is performed. The conjunctival flap is now replaced and a bandage applied.

As far as the Lagrange procedure is concerned, you will remember that after eserinization an oblique incision is made through the sclera by means of a narrow Graefe knife and a large conjunctival flap secured.

Being hooked at one of its extremities the iron became entangled in either the inferior oblique or external rectus muscles, and completely avulsed the eyeball upon the cheek. The real damage could not be estimated, as the patient never returned after the muscle was clipped off close to its conjunctival insertion.

Unlike the trephine operation which was evolved from it, the Lagrange operation requires the same kind of an opening of the eyeball as required for a well executed iridectomy, and a properly placed section entirely in scleral tissue, with a good sized conjunctival flap, are elements which enter into the ultimate success or failure of the procedure.

Many authors, for example, Darier, Grandclement and others, are strong in their recommendation of adrenalin, particularly if this drug is added to the various myotic mixtures, and yet adrenalin is certainly not without danger in the treatment of glaucoma. McCallan has seen a number of instances of striking increase of intra-ocular tension following this instillation in the conjunctival sac.

The technique of the operation is even more difficult and exacting than in the performance of the trephine operation, and it also compares unfavorably in safety. The advisability of removing the conjunctival flap, as advocated by Dr.

Furthermore, the possibilities of damage by hemorrhage from the choroidal or retinal vessels, delayed formation of the anterior chamber and adhesion of the capsule of the lens to the wound, and the injurious effects of even slight trauma subsequent to the operation, including loss of vitreous, are increased by omitting the conjunctival flap.

Two of them now had fever in the continued form, and became jaundiced, the whites or conjunctival membrane of their eyes becoming as yellow as saffron; and a third suffered from an attack of mania. He came to his companions one day, and said, "Remain well. I am called away by the gods!" and set off at the top of his speed. The young men caught him before he had gone a mile, and bound him.