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Updated: June 1, 2025
Ulcerative endocarditis was for a long time believed to be inevitably fatal; it is now known that a small proportion of patients with this disease recover. Children occasionally suffer from it, but it is generally a disease of middle adult life. Chorea may bear an apparent causal relation to it in rare instances.
The differences in inflammation in the two cases is really one of degree, and the classification is made to coincide with this probable fact. it is, of course, clinically recognized that endocarditis following certain diseases, especially rheumatism, is of the simple or mild type, while that termed ulcerative endocarditis may occur apparently as a primary or general infection, and the causative bacteria, as a rule, are readily discovered in the blood.
Meningitis, pneumonia, diphtheria, typhoid fever and rarely rheumatism may all cause this severe form of endocarditis. Ulcerative endocarditis was first described by Kirkes in 1851, was later shown to be a distinctive type of endocarditis by Charcot and Virchow, and finally was thoroughly described by Osler in 1885.
No ulcerative process responds so readily to medicinal treatment as the syphilitic ulcer does to the intra-venous administration of arsenical preparations of the "606" or "914" groups or to full doses of iodide of potassium and mercury, and the local application of black wash.
The first mastication in the ox is three times quicker than in horses, but the process of rumination is slow and thorough. STOMATITIS. Simple inflammation of the mouth is frequently met with in horses. Ulcerative or infectious inflammation commonly occurs in young, and occasionally in old, debilitated animals.
The bright red rim round the insertion of the cord, with inflammatory thickening and slight purulent secretion, may be considered as evidence of live birth, and the stage at which the separation of the cord by ulcerative process has arrived will point to the probable duration of time the child has existed after birth.
Ulcerative endocarditis may develop on a mild endocarditis, with disintegration of tissue and deep points of erosion, and there may be little pockets of pus or little abscesses in the muscle tissue. If such a process advances far, of course the prognosis is absolutely dire.
No symptoms developed, but six weeks later, the child had an attack of ulcerative stomatitis, from which it seemed to be recovering nicely, when suddenly it ejected two ounces of bright red blood in clots, and became collapsed out of proportion to the loss of blood. Under treatment, it rallied somewhat, but soon afterward it ejected four ounces more of blood and died in a few minutes.
"it must also be taken into the account, that, although in the canine cancer ulceration does not often reappear in the intermediate part, when the operation has been judiciously performed, yet, when the constitution has been long affected with this ulcerative action, it is very apt to show itself in some neighbouring part soon after."
Later on in the same family there was a case of la grippe, in which for several years there had been chronic, ulcerative bronchitis that bid defiance to blisters and inhalations, the various specifics of another forceful predecessor, who also was a believer in large doses and full rations of alcoholized milk.
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