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And leaving out of sight all that lies in the dark beyond, surely if we sum up the lamed aspirations, the perverted tastes, the ossifying of noble emotions, the destruction of the balance of the nature, the blinding of the eye of the soul, the lowering and narrowing of the whole nature, and many another wound to the best in man that come as the sure issue of evil deeds, we do not need to doubt that every sinful man is miserably 'holden with the cords of his sin. Life is the time for sowing, but it is a time for reaping too, and we do not need to wait for death to experience the truth of the solemn warning that 'he who soweth to the flesh shall of the flesh reap corruption. Let us, then, do no deeds without asking ourselves, What will the harvest be? and if from any deeds that we have done we have to reap sorrow or inward darkness, let us be thankful that by experience our Father is teaching us how bitter as well as evil a thing it is to forsake Him, and cast off His fear from our wayward spirits.

The disease is not attended with any disturbance of the general health; the pathological changes are the same as in infantile rickets, but are for the most part confined to the ossifying junctions, especially those which are most active during adolescence, for example at the knee-joint.

The lesions in infancy epiphysitis, bossing of the skull, and craniotabes have been referred to in the chapter on inherited syphilis. Epiphysitis or Syphilitic Perichondritis. The first of these terms is misleading, because the lesion involves the ossifying junction and the shaft of the bone, and the epiphysis only indirectly.

When there is marked rarefaction of the bone at the ossifying junction, the epiphysis is liable to be separated epiphysiolysis. The separation usually takes place through the young bone of the ossifying junction, and the surfaces of the diaphysis and epiphysis are opposed to each other by irregular eroded surfaces bathed in pus.

The post-mortem appearances are those of pyæmia. Differential Diagnosis. Acute osteomyelitis is to be diagnosed from infections of the soft parts, such as erysipelas and cellulitis, and, in the case of the tibia, from erythema nodosum. Tenderness localised to the ossifying junction is the most valuable diagnostic sign of osteomyelitis.

Do you still think you will be in danger of ossifying?" Adams let the question rest while he asked one of his own. "How do you come to be mixed up in it, Jack? A week ago some one told me you were going to South America to build a railroad in the Andes. What switched you?" Winton shook his head. "Fate, I guess; that and a wire from President Callowell of the Utah offering me this.

The disease commences and is most intense in the marrow of the ossifying junction at one end of the diaphysis; it may commence at both ends simultaneously bipolar osteomyelitis; or, commencing at one end, may spread to the other. The changes observed are those of intense engorgement of the marrow, going on to greenish-yellow purulent infiltration.

Chondroma, or enchondroma, is a cartilaginous tumor occurring principally where cartilage is normally found, but sometimes in regions containing no cartilage. Enchondroma may be composed of osteoid tissue, such as is found in the ossifying callous between the bone and the periosteum, and, according to Virchow, then takes the name of osteochondroma.

Any diseased process that affects the periosteum is spoken of as periostitis; the term osteomyelitis is employed when it is located in the marrow. The term epiphysitis has been applied to an inflammatory process in two distinct situations namely, the ossifying nucleus in the epiphysis, and the ossifying junction or metaphysis between the epiphysial cartilage and the diaphysis.

The disorder mainly affects the ossifying junctions of the long bones of the extremities, the vertebral border of the scapula, and the cristal border of the ilium.