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There is an undue pressure upon all between-vessel structures, a pressure that must lessen the nutrient supply more or less, according to its degree. The death of parts in boils and abscesses is due, I believe, to strangulation of the nerve-supply. The bloodvessels are elastic, and capable of contraction and dilatation, a matter regulated by the brain.

The action of this delicate apparatus is readily disturbed, if the nerve-supply to it is disordered by irritation in some distant organ, and then the breathing is accompanied by the peculiar sound of spasmodic croup, or in older children this may show itself in a different way, as in the loud, barking cough heard in some cases of constipation, or of disordered digestion; or another illustration of it is furnished by the loud, long breath the 'hoop, which gives its name to hooping-cough.

Ovulation; Etiology of Menstruation; Uterine Nerve-supply; the Function of the Uterus; Stages of the Menstrual Cycle; Average Duration of the Menstrual Flow; Character of tahe Flow; Relation of Ovulation to Menstruation; the Menstrual Wave; Definition of Menstruation; Premomitory Symptoms of the Flow; Hygiene of Menstruution.

Bed-sores are most frequently met with in old and debilitated patients, or in those whose tissues are devitalised by acute or chronic diseases associated with stagnation of blood in the peripheral veins. Any interference with the nerve-supply of the skin, whether from injury or disease of the central nervous system or of the peripheral nerves, strongly predisposes to the formation of bed-sores.

The general treatment is conducted on the same lines as on other forms of pyogenic infection. Definitions Clinical examination of an ulcer The healing sore. Classification of ulcers A. According to cause: Traumatism, Imperfect circulation, Imperfect nerve-supply, Constitutional causes B. According to condition: Healing, Stationary, Spreading. Treatment.

Gradually, however, the idea took its place in the current knowledge of nerve physiology, and in time it came to be understood that what happens in the case of the heart nerve-supply is only a particular case under a very general, indeed universal, form of nervous action.

The acute bed-sore is a rapidly progressing form of ulceration, often amounting to gangrene, of portions of skin exposed to pressure when their trophic nerve-supply has been interfered with. [Illustration: FIG.

The chronic and intractable character of the ulcer is due to interference with the trophic nerve-supply of the parts, and to the fact that the epithelium of the skin grows in and lines the track leading down to the deepest part of the ulcer and so prevents closure.

This is especially liable to occur when the nutrition of the skin is depressed by any interference with its nerve-supply, such as follows injuries to the spine or peripheral nerves, disease of the brain, or acute anterior poliomyelitis. When the splint is removed the skin pressed upon is found to be of a pale yellow or grey colour, and is surrounded by a ring of hyperæmia.

In the other case there is not merely the congestion of the windpipe, the disturbed nerve-supply, and the swollen state of the membrane; but in connection with the influence of the special poison of diphtheria, a deposit takes place at the back of the throat, whence it extends to the windpipe, and in many instances even far beyond it, blocking up its canal, and mechanically excluding the entrance of air.