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Buret traces the origin of the word syphilis from sun, with, and filia, love, the companion of love; which means in plain language that the pox is a disease transmitted more especially by venereal relations. The first great epidemic of syphilis occurred between 1493 and 1496, and attacked all ranks, neither the Church nor the Crown being spared.
Bloch regards Ruy Diaz de Isla, a distinguished Spanish physician, as the weightiest witness for the Indian origin of the disease, and concludes that it was brought to Europe by Columbus's men from Central America, more precisely from the Island of Haiti, to Spain in 1493 and 1494, and immediately afterwards was spread by the armies of Charles VIII in an epidemic fashion over Italy and the other countries of Europe.
In 1493 the representation of eclogues formed part of the revels prepared by Alexander VI for the marriage of Lucrezia Borgia with Giovanni Sforza, Lord of Pesaro, and this was again the case when, having been divorced from Giovanni, and her second husband having perished by the assassin's dagger, she finally in 1502 became the wife of Alfonso d'Este, heir to the duchy of Ferrara.
CLASS IV. The next class to be considered is that in which the individuals are separate and well formed, except that the point of fusion is a common part, eliminating their individual components in this location. The pygopagous twins belong in this section. According to Bateman, twins were born in 1493 at Rome joined back to back, and survived their birth.
From the time that the news of the discovery made by Columbus had reached England, that is to say, probably in 1493, John and Sebastian Cabot prepared the expedition at their own expense, and set out at the beginning of the year 1494, with the idea of reaching Cathay, and finally the Indies.
Girolama Farnese, Giulia 's sister, wrote to her husband, Puccio, from Casignano, October 21, 1493, "You will have received letters from Florence before mine reaches you and have learned what benefices have fallen to Lorenzo, and all that Giulia has secured for him, and you will be greatly pleased."
It was Philip the Fair who, wishing to centralize the scattered efforts of these societies, established at Malines, in 1493, a sovereign chamber, of which he appointed his chaplain, Pierre Aelters, sovereign prince. With an admixture of religion, in accordance with the spirit of the Middle Ages, the sacred number was fifteen. There were fifteen members.
Word came to Barcelona that King John of Portugal was equipping a large armament to obtain a share of the new realms in the west, and all haste was made to anticipate this dangerous rival by sending Columbus again to the New World. On the 25th of September, 1493, he set sail with a gallant armament, which quite threw into the shade his three humble caravels of the year before.
In 1481, Don Juan, having killed an officer of the king of Naples, was compelled to leave Rome, and escaped to Como with his wife and his son; but having left that city to seek his fortune, he died while traveling with Christopher Columbus in the year 1493. Marco Antonio became a noted poet of the school of Martial, and was secretary to Cardinal Pompeo Colonna.
After this expedition, so fruitful in results, voyages of discovery became rather less frequent for some years; the Spaniards being occupied in asserting their supremacy in the countries in which they had already founded colonies. The colonization of Hispaniola had commenced in 1493, when the town of Isabella was built.
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