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One of the most salient characteristics of the Amniotes is the complete loss of the gills. The Protamniote itself must have entirely abandoned water-breathing. But we do not find in the embryos of the Amniotes any trace of gill-leaves, or of real respiratory organs on the gill-arches. It is very probable that the urinary bladder of the Dipneusts is the first structure of the allantois.

The former pain at the pit of the stomach recurs by intervals, as the bile-stone is pushed against the neck of the duct; like the paroxysms of the stone in the urinary bladder, the other is a more dull and constant pain. Where these bile-stones are too large to pass, and the bile-ducts possess their sensibility, this becomes a very painful and hopeless disease.

Everything, then, appears to show that the same substance, derived from urinary excretions, yields, according to the mode in which its ultimate particles are grouped, the metallic red of the Phanæus, as well as the white, the dull red and the black of the Sacred Beetle.

When any one drinks a moderate quantity of vinous spirit, the whole system acts with more energy by consent with the stomach and intestines, as is seen from the glow on the skin, and the increase of strength and activity; but when a greater quantity of this inebriating material is drank, at the same time that the lacteals are excited into greater action to absorb it; it frequently happens, that the urinary branch of absorbents, which is connected with the lacteals by many anastomoses, inverts its motions, and a great quantity of pale unanimalized urine is discharged.

Some, who had been shot through the mouth or neck, were unable to swallow, and we had to push a rubber tube down through the bloody froth that filled their throats, and pour water into their stomachs through that; some lay on the ground with swollen bellies, suffering acutely from stricture of the urinary passage and distention of the bladder caused by a gunshot wound; some were paralyzed from the neck down or the waist down as a result of injury to the spine; some were delirious from thirst, fever, and exposure to the sun; and some were in a state of unconsciousness, coma, or collapse, and made no reply or sign of life when I offered them water or bread.

Thus by the muscular action resulting from pain we are protected against heat and cold; against too powerful light; against local anemia caused by prolonged pressure upon any portion of the body. So, too, pain of greater or less intensity compels the required emptying of the pregnant uterus and the evacuation of the intestine and the urinary bladder.

It is formed in the intestine of the sperm-whale, and contains fragments of the hard parts of cuttle-fishes, which are the food of these whales. "Hair-balls" are formed in the intestines of various large vegetarian animals and occasionally stony concretions of various chemical composition are formed in the urinary bladder of various animals, as well as of man.

The kinetic system does not directly circulate the blood, nor does it exchange oxygen and carbon dioxid; nor does it perform the functions of digestion, urinary elimination, and procreation; but though the kinetic system does not directly perform these functions, it does play indirectly an important role in each, just as the kinetic system itself is aided indirectly by the other systems.

Among the important changes of the vertebrate organisation that marked the rise of the first Amniotes from salamandrine Amphibia during this period the following three are especially noteworthy: the entire disappearance of the water-breathing gills and the conversion of the gill-arches into other organs, the formation of the allantois or primitive urinary sac, and the development of the amnion.

Perhaps there may have been a wound of the bladder, although no external haemorrhage has appeared, but the blood coagulating gradually in the bladder has occasioned an obstruction or narrowing of the urinary passage. Or possibly the blood from a renal haemorrhage has descended into the bladder and obstructs the urethra.