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II. On Osteomyelitis. Single observation. I have but one observation relating to this severe disease, and in this Dr. Lannelongue took the initiative. The monograph on osteomyelitis published by this learned practitioner is well known, with his suggestion of the possibility of a cure by trephining the bone and the use of antiseptic washes and dressings.

Even under favourable conditions, and with the continuous effort at reconstruction of the bone by Nature's method, the return to normal is often far from perfect, and there usually remains a variable amount of hyperostosis and sclerosis and sometimes curving of the bone. Under less favourable conditions, the late results of osteomyelitis may be more serious.

#Cysts of Bone.# With the exception of hydatid cysts, cysts in the interior of bone are the result of the liquefaction of solid tissue; this may be that of chondroma, myeloma, or sarcoma, but more commonly of the marrow in osteomyelitis fibrosa. Definition of terms Ankylosis.

Before the stage of cold abscess is reached, the localised swelling is to be differentiated from a gumma, from chronic forms of staphylococcal osteomyelitis, from enlarged bursa or ganglion, from sub-periosteal lipoma, and from sarcoma. Most difficulty is met with in relation to periosteal sarcoma, which must be differentiated either by the X-ray appearances or by an exploratory incision.

The size of the abscess ranges from that of a cherry to that of a walnut, but specimens in museums show that, if left to Nature, the abscess may attain much greater dimensions. The affected bone is not only thicker and heavier than normal, but may also be curved or otherwise deformed as a result of the original attack of osteomyelitis. The clinical features are almost exclusively local.

We shall restrict the term to inflammation in the first of these situations. Inflammation at the ossifying junction is included under the term osteomyelitis. The term rarefying ostitis is applied to any process that is attended with excessive absorption of the framework of a bone, whereby it becomes more porous or spongy than it was before, a condition known as osteoporosis.

Cases are sometimes met with in which relapses recur at regular intervals for several years, the tendency, however, being for the attacks to become milder as the virulence of the organisms becomes more and more attenuated. Clinical Features. Osteomyelitis in a patient over twenty-five is nearly always of the relapsing variety.

Similar varieties of osteomyelitis are met with that do not, like the acute forms, go on to suppuration or to death of bone, but result in thickening of the bone affected, both on the surface and in the interior, resulting in obliteration of the medullary canal.

It should be excised widely; in the lower extremity when there is also extensive destruction of tissue from an antecedent chronic ulcer or osteomyelitis, it may be better to amputate the limb. Injuries. When a nail is contused or crushed, blood is extravasated beneath it, and the nail is usually shed, a new one growing in its place.

Any diseased process that affects the periosteum is spoken of as periostitis; the term osteomyelitis is employed when it is located in the marrow. The term epiphysitis has been applied to an inflammatory process in two distinct situations namely, the ossifying nucleus in the epiphysis, and the ossifying junction or metaphysis between the epiphysial cartilage and the diaphysis.