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Updated: May 23, 2025


X-ray appearances in periosteal tubercle: the surface of the cortical bone in the area of disease is roughened and irregular by erosion, and in the vicinity there may be a deposit of new bone on the surface, particularly if a sinus is present and mixed infection has occurred; in syphilis the shadow of the bone is denser as a result of sclerosis, and there is usually more new bone on the surface hyperostosis; in periosteal sarcoma there is greater erosion and consequently greater irregularity in the contour of the cortical bone, and frequently there is evidence of formation of bone in the form of characteristic spicules projecting from the surface at a right angle.

Even under favourable conditions, and with the continuous effort at reconstruction of the bone by Nature's method, the return to normal is often far from perfect, and there usually remains a variable amount of hyperostosis and sclerosis and sometimes curving of the bone. Under less favourable conditions, the late results of osteomyelitis may be more serious.

When there is hyperostosis and sclerosis, the shaft appears denser and broader than normal, and the contour is uneven or wavy. When there is a central gumma, the shadow is interrupted by a rounded clear area, like that of a chondroma or myeloma, but there is sclerosis round about. Diagnosis.

When hyperostosis and sclerosis of the bone is attended with severe pain which does not yield to blistering, the periosteum may be incised and the sclerosed bone perforated with a drill or trephine.

Even at a distance from the actual necrosis there is formation of new bone by the marrow; the medullary canal is often obliterated, and the bone becomes heavier and denser sclerosis; and the new bone which is deposited on the original shaft results in an increase in the girth of the bone hyperostosis.

Hyperostosis and sclerosis are frequently met with in combination, a condition that is well illustrated in the femur and tibia in tertiary syphilis; if the subject of this condition is confined to bed for several months before his death, the sclerosis may be undone, and rarefaction may even proceed beyond the normal, the bone becoming lighter and richer in fat, although retaining its abnormal girth.

The new bone on the surface sometimes takes the form of a diffuse encrustation of porous or spongy bone as in secondary syphilis, sometimes as a uniform increase in the girth of the bone hyperostosis, sometimes as a localised heaping up of bone or node, and sometimes in the form of spicules, spoken of as osteophytes.

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