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Updated: June 26, 2025
Introspective observation of pre-criminal states of mind by so-called normal persons reveals that in many of them there is an impairment of reason and will power, in others an exaltation amounting almost to hysteria. What are these but endocrine states of the cells, experimentally reproducible by increasing or decreasing the influence of the thyroid, the adrenals, the pituitary?
When the adrenals fail, as they do readily in these labile adrenocentrics, it is as if the adrenals were cut out of the body. And it has been repeatedly shown that extirpation of the adrenals is immediately followed by degeneration and breakdown of the brain cells. These facts explain the reactions of Lieut.
Now take the burning up of sugar in the organism, the great material source of energy, which is controlled by the pancreas, the adrenals and the liver, the thyroid and the pituitary. Together they form the directorate of sugar metabolism.
The adrenals tire, becoming incapable of dumping massive amounts of stress-handling hormones or of repeating that effort time after time without considerable rest in between. The consequences of these inter-dependent deterioration's is a cascade of deterioration that contributes to even more rapid deterioration's. The name for this cascading process is aging. Its inevitable result death.
Infections in adrenocentrics use up the content of the adrenals as rapidly as physical exhaustion or emotion.
As we believed that the adrenals were intimately associated with the brain in its activities, we concluded that the adrenals also must have been affected by each of these agents.
Some women are rendered unstable by the process, others are completely transformed, and still others adapt themselves, with little or no discomfort, to the new situation. The response to the revolution in the cell-republic of the castrate by the other endocrines, the thyroid, the pituitary, and the adrenals, determines which it is to be.
Neither the brain, the adrenals, the liver, nor the muscles, however, nor all of these together, have the power to change the rate of the expenditure of energy; to make possible the increased expenditure in adolescence, in pregnancy, in courting, and mating, in infections. No one of these organs, nor all of them together, can act as a pace-maker or sensitizer.
For the internal secretion of the thyroid has a selective affinity for the autonomic or activating system, while that of the adrenals has a selective affinity for the sympathetic or inhibiting system.
Over these organs the thyroid, the adrenals, the hypophysis the contact ceptors have no control. Prolonged laboratory experimentation seems to prove this postulate. This is a statement of far-reaching importance and is the key to an explanation of many chronic diseases diseases which are associated with the intense stimulation of the distance ceptors in human relations.
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