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Updated: June 26, 2025
Were they alive today, and willing to submit themselves to scientific scrutiny, the X-ray would tell us of the state of the pituitary and thymus in them, chemical examinations of the blood the condition of the thyroid and adrenals, detailed investigation of the body and mind a flood of light upon their maladies as well as their personalities.
Crile and his co-workers have shown that in surgical shock histological changes occur in the cells of the brain, the adrenals, and the liver, and that these are identical, whatever be the cause that leads to the exhaustion of the energy-transforming mechanism.
And as a matter of fact, a good number of observations conspire for the idea that a certain number of neurasthenics are suffering from insufficiency of the adrenal gland. The chronic state of the acute phenomenon, known as the nervous breakdown, really represents in them a breakdown of the reserves of the adrenals, and an elimination of their factor of safety.
It meant a most delicate balance between his ante-pituitary, post-pituitary, adrenals and thyroid. He was an orator, politician, historian, conqueror, and statesman. That his thyroid functioned well can be deduced from a career which involved more than three hundred personal triumphs as recognition from his native city.
As a result of these researches we are able to state that the H-ion concentration of the blood its acidity is increased by excessive muscular activity; excessive emotional excitation; surgical shock; in the late stages of infection; by asphyxia; by strychnin convulsions; by inhalation anesthetics; after excision of the pancreas, and in the late stages of life after excision of the liver and excision of the adrenals.
On the other hand, if the nerve supply to the adrenals had been previously divided, or if the adrenals had been previously excised, then the Cannon test was negative after the administration of each of the foregoing adequate stimuli.
To prove this relation, we administered the above-mentioned stimuli to animals and studied their effects upon the adrenals by functional, histologic, and surgical methods, the functional tests being made by Cannon's method. Functional Study of the Adrenals. If this second test was negative, a small amount of adrenalin was added.
Or if the cortical secretion pours in an overwhelming amount of its secretion from the first into the blood there will be no fear, but anger immediately. Habitually charging and fearless animals like the bison, bull, tiger, or lion have a relatively larger cortex in their adrenals. Habitually fleeing and fearful animals, like the rabbit, have a small cortex and a wide medulla in their adrenals.
The chemical mechanism of the instincts described: sex libido, passion and jealousy in relation to the ovaries and testes, fear and anger in relation to the adrenals, sympathy and curiosity in relation to the pituitaries, suggests that a similar explanation will hold for the dynamics of the other instincts.
Without their own adrenals, the cats could not live more than a short time By finding out how much extract was required to keep the cats from failing, he could measure the strength of the particular batch. Dr. Pottenger's cats were economically valuable so he made every effort to keep them healthy, something that proved to be disappointingly difficult.
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