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The Pineal Era, from the second to the tenth to fourteenth years, remains to be investigated from a number of viewpoints interesting to the parent, the educator, and the student of puericulture. Precocity is directly related to early involution of the pineal. For just as the thymus involutes at the second year, the pineal atrophies before the onset of adolescence.

Also, the thymus has been discovered diseased in certain mysterious progressive muscular wastings. A remarkable fatigability of muscles, which appears after the slightest exertion, is a feature. The feeding of thymus has caused muscle cramps which apparently depends upon an increased excitability of the muscle nerve endings.

Modern knowledge of these chemical substances, circulating in the blood, and affecting every cell of the body, dates back scarce half a century. But already the paths blazed by the pioneers have led to the exploration of great countries. The thyroid gland, the pituitary gland, the adrenal glands, the thymus, the pineal, the sex glands, have yielded secrets.

The endocrine criteria, more exact and concrete, divide them into the adrenal centered, the thyroid centered, the thymus centered, the pituitary centered, the gonad centered, and their combinations. An adrenal personality is one dominated by the ups and downs of his adrenal gland. In the large, the curve of his life is the curve of secretion by this gland, both of its Cortex and medulla.

As vital force drops, the overall efficiency of all the body's organs correspondingly decline. The pancreas creates less digestive enzymes; the thymus secretes less of its vital hormones that mobilize the immune system; the pituitary makes less growth hormone so the overall repair and rebuilding of cells and tissues slows correspondingly; and so forth.

To me, a cancer is a cancer is a cancer, and there is only one kind: it is an immune system collapse, consequence of the deadly triangle of weak spleen, thymus and liver, plus a toxic large intestine and weak pancreas. That organ profile is found in skin cancer, prostate cancer, leukemia, brain cancer, cancer of what have you.

As a consequence, to hold the sex stimulating glands in check, there had to appear others, restraining them and so preventing sex precocity. These are the thymus and pineal. So closely are they all related that insufficient action of the thyroid, pituitary or adrenals may cause atrophy of the ovaries and uterus, with abolition of genital function.

Every individual born among the vertebrates, for example, must have a certain definite amount and percentage of pituitary gland, anterior and posterior, pineal, thyroid, parathyroid, thymus, adrenal, pancreas, interstitial and so on. One obtains at once from the contrasts of such figures some idea of the possibilities.

The brain and nervous system complete their growth in mass by the end of the fourth year. Recall the experiments of Gudernatsch working with tadpoles, who showed that feeding with thymus produced giant tadpoles whose metamorphosis into frogs was inhibited, while feeding thyroid produced frogs the size of flies. Differentiation occurred without the preliminary increase in mass usual.

It is situated beneath the muscles of the neck on the sides of "Adam's apple" and below it. It undergoes great enlargement in the disease called goitre. The thymus is also a blood gland. It is situated around the windpipe, behind the upper part of the breastbone. Until about the end of the second year it increases in size, and then it begins gradually to shrivel away.