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Updated: May 10, 2025


Walter Reed was a favorite pupil of Professor Welch, a warm friend of all of us, and a frequent visitor to our laboratories. Dr. Jesse Lazear, who had been my house physician, had worked with Dr. Thayer and myself at malaria, and gave up the charge of my clinical laboratory to join the commission. Matthew Carey: A Short Account of the Malignant Fever, Philadelphia, 1793.

In the third case, that of Dr. Lazear, the facts are stated in the report of the board as follows: Case 3. Dr. No appreciable disturbance of health followed this inoculation. As Dr.

But the first to announce clearly the mosquito theory of the disease was Carlos Finlay of Havana. Dr. Walter Reed, Professor of Bacteriology in the Army Medical School, was placed in charge: Dr. Carroll of the United States Army, Dr. Agramonte of Havana and Dr. Jesse W. Lazear were the other members. At the Johns Hopkins Hospital, we were deeply interested in the work, as Dr.

"Thus at Camp Lazear, of seven nonimmunes whom we attempted to infect by means of the bites of contaminated mosquitoes, we have succeeded in conveying the disease to six, or 85.71 per cent.

The dreaded vomit soon appeared. I was too weak to see him again in that condition, and there was nothing that I could do to help him. "Dr. Lazear left a wife and two young children, one of whom he had never seen." These experiments and many others like them conducted on soldiers and Spanish immigrants proved that this particular mosquito would transmit the disease under certain conditions.

These were placed at a distance of about twenty feet from each other, and numbered 1 to 7 respectively. Camp Lazear was established November 20, 1900, and from this date was strictly quarantined, no one being permitted to leave or enter camp except the three immune members of the detachment and the members of the board.

Lazear was stricken, and died in convulsions just one week later, after several days of delirium with black vomit. Such is yellow fever. "He was bitten by a stray mosquito while applying the other insects to a patient in one of the city hospitals. He did not recognize it as a Stegomyia, and thought it was a Culex.

Lazear applied the same mosquito, with three others, to another individual who suffered a comparatively mild attack and was well before I had left my bed. It so happened that I was the first person in whom the mosquito was proved to convey the disease. "On the eighteenth of September, five days after I was permitted to leave my bed, Dr.

On the afternoon of July 27, 1900, I submitted myself to the bite of an infected mosquito applied by Dr. Lazear. The insect had been reared and hatched in the laboratory, had been caused to feed upon four cases of yellow fever, two of them severe, and two mild.

This board, which came to be known as the Yellow Fever Commission, was composed of Drs. Walter Reed, James Carroll, Jessie W. Lazear and Aristides Agramonte of the United States Army. Agramonte was a Cuban and an immune, the others were non-immunes. Dr.

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