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Updated: June 12, 2025


Consequently, this ductless gland a gland, that is to say, which has no obvious canal by which it throws off any product of its activity must elaborate some material that is necessary to the health of the organism and is imparted to the blood. That material, whatever it may be, is termed an "internal secretion." Some of the internal secretions have turned out to be of singular value medicinally.

There are possibilities the imagination may envisage. One may suppose such a cretin, with all his other ductless glands intact, grown successfully to manhood under careful medical guidance. No one but himself is aware of his affliction, outside of his medical advisers. Luck aids him to rise in the world, or perhaps he has been born with a spoon of the precious metals in his mouth.

There are certain instruments used by scientists so delicate that they have to be wrapped in cotton wool and kept in ductless places, and so sensitive that the slightest shock will derange them. And there are certain souls which cannot stand the jars of life souls created to register thoughts and sentiments too fine for those of coarser construction.

As within a corporation there are factions and cliques, influences that always work together, and forces that are always pulling in opposite directions, so within the interlocking directorate of the ductless glands there are antagonisms and inhibitions, co-operations and compensations.

The activities of the ductless glands and their hormones equally serve both ends in ways that cannot be distinguished. "The individual metabolism," as a distinguished authority in this field has expressed it, "is the reproductive metabolism."

Indeed, it is far more a matter of the digestion, the muscles, and the ductless glands, than it is of the brain, or even of the nervous system. It is, therefore, idle to endeavor either to treat or try to prevent it by measures directed to the head, the brain, or even the nervous system as such.

Together with the other ductless glands, they decide the advance or halt, forward or retreat, tension or relaxation, charge and discharge, of the visceral involuntary muscle blood vessel combination which is at the core of life. Here again they emerge as the directorate.

He let pass all sorts of misprints in his article on the Ductless Glands for the Encyclopaedia Scotica, he was always losing the thread of his discourse in his lectures at the London Institution and University College; and he spent too much of his valuable time writing hugely long letters on all sorts of subjects to David Williams. David or Vivie replied much more laconically.

They are called endocrine glands or organs, and their chemical contributions to the blood are known as hormones. Sometimes those which do nothing but furnish these secretions are spoken of as "ductless glands," from their structure. Some authorities think that "every cell in the body is an organ of internal secretion", and that thus each influences all the others.

Mental defect and feeble-mindedness are conceived essentially as retardation, arrest of development, differing in degree so that the victim is either an idiot, an imbecile, feeble-minded or a moron, according to the relative period at which mental development ceases. Scientific research into the functioning of the ductless glands and their secretions throws a new light on this problem.

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