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It has been remarked that certain villages in England are in like manner much more subject to this visitation than others. Dr. Unanue states that hydrophobia was first known in South America in 1803: this statement is corroborated by Azara and Ulloa having never heard of it in their time. Dr. Unanue says that it broke out in Central America, and slowly travelled southward.

Nearer Buenos Ayres, on the road from that place to San Isidro, there are extensive beds, as I am informed by Sir Woodbine Parish, of the Azara labiata, lying at about forty feet above the level of the river, and distant between two and three miles from it.

At Valdivia there is some sandstone with imperfect casts of shells, which POSSIBLY may belong to the recent period: parts of the boulder formation and the shingle-beds on the lower plains of Patagonia probably belong to this same period, but neither are fossiliferous: it also so happens that the great Pampean formation does not include, with the exception of the Azara, any mollusca.

Azara has also observed with astonishment this change: he is likewise much perplexed by the immediate appearance of plants not occurring in the neighbourhood, on the borders of any track that leads to a newly- constructed hovel. Does this not partly explain the circumstance? We thus have lines of richly manured land serving as channels of communication across wide districts.

The port of La Guayra alone exported annually from 1789 to 1792, 70,000 or 80,000 hides, entered in the custom-house books, scarcely one-fifth of which was sent to Spain. The exportation from Buenos Ayres, at the end of the eighteenth century, was, according to Don Felix de Azara, 800,000 skins.

Azara says "Je crois que la quantite annuelle des pluies est, dans toutes ces contrees, plus considerable qu'en Espagne." Hence we must look to some other and unknown cause.