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An obliquity of the bone may result when one half of the epiphysial cartilage is destroyed and the other half continues to form bone, giving rise to such deformities as knock-knee and club-hand. Deformity may also result from vicious union of a pathological fracture, permanent displacement of an epiphysis, contracture, ankylosis, or dislocation of the adjacent joint.

There were printed bills on the gate and on bits of carpet hanging out of the windows, announcing a sale by auction of the Household Furniture and Effects, next week. The House itself was to be sold as old building materials, and pulled down. LOT 1 was marked in whitewashed knock-knee letters on the brew house; LOT 2 on that part of the main building which had been so long shut up.

The patient is easily tired, complains of pain in the bones, and, unless care is taken, deformity is liable to ensue. There can be no doubt that adolescent rickets plays an important part in the production of the deformities which occur at or near puberty, especially knock-knee and bow-knee.

A very high proportion of older children suffering from the graver neuroses, such as chorea, syncopal attacks, phobias, tics, and so forth, show defective physical development. Scoliosis, lordosis, knock-knee, flat foot, pigeon chest, albuminuria, cold and cyanosed extremities, are the rule rather than the exception.

In the lower extremity, for example, any condition which disturbs the static equilibrium of the limb as a whole would appear to predispose to the disease in one or other of the joints. The static equilibrium may be disturbed by such deformities as flat-foot or knock-knee, and badly united fractures of the lower extremity.

In rickets, for example, the formation of new bone may take place unequally, and may go on more rapidly in one half of the disc than in the other, with the result that the axis of the shaft comes to deviate from the normal, giving rise to knock-knee or bow-knee.