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Updated: May 16, 2025
All these considerations were not only powerful determinants to Southernism, but in themselves balm to the conservative heart, and hardly less so to that overwhelming section of educated liberal opinion in this country, which, genuinely liberal though its politics may be according to the English standard, abhors all approach towards what is termed "Americanizing our institutions," and is fully as eager as the strictly conservative class to lay hold of any facts which may make monarchy appear a stable, and republicanism an unstable system.
We then considered the nature of scientific laws, and found that, instead of stating that one event A is always followed by another event B, they stated functional relations between certain events at certain times, which we called determinants, and other events at earlier or later times or at the same time.
In the course of their growth and development these determinants are subject to diverse influences due to the position they happen to occupy, to their quality, to changes in the nutritive conditions, and so on. Through these influences variations in the determinants may be brought about.
If the absence of pigment from the lower side in normal Flat-fishes is due to the absence of light, how is it that the pigmentation persists on the lower side of ambicolorate specimens, which is no more exposed to light than in normal specimens? The answer is that in the mutants the determinants for pigmentation are united with the determinants for the lower side of the fish.
In such knowledge of given or historic fact lie the natural determinants of his conduct, in such knowledge alone lies the condition of his freedom and his good. But this does not mean that Moral Philosophy has not still much to learn from Aristotle's Ethics.
This is what Goethe meant when he said that substantiality was the category of the epic, causality of the drama, although, of course, this distinction is not absolute. Fate, in the sense of the non-human determinants of man's career, can show its hand. In the Odyssey, for example, shipwreck and the interference of the gods are factors as decisive as Odysseus' courage and cunning.
We do not secretly chafe at "Whom did you see?" without reason. But the drift away from whom has still other determinants. The words who and whom in their interrogative sense are psychologically related not merely to the pronouns which and what, but to a group of interrogative adverbs where, when, how all of which are invariable and generally emphatic.
The reproductive cells also undergo division and increase in number, and when they separate from the new individual and unite in fertilisation they still possess all the determinants of the fertilised ovum from which they are descended. Heredity thus continues from gamete to gamete, not from zygote to soma, and then from soma to gamete.
We may suppose that different parts of the body are represented in the gametes by different determinants or factors, and therefore it is possible that these factors may be separated.
The theory proposed by me in 1908 was that we have within the gonads numerous gametocytes whose chromosomes contain factors corresponding to the different parts of the soma, and that factors or determinants might be stimulated by products circulating in the blood and derived from the parts of the soma corresponding to them.
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