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On the other hand, the cartilage may undergo calcification or ossification. The most important transition of all is that into sarcoma, the so-called malignant chondroma or chondro-sarcoma, which is associated with rapid increase in size, and parts of the tumour may be carried off in the blood-stream and give rise to secondary growths, especially in the lungs.

A study of the internal organs has been made by Ruffer, who has shown that arterio-sclerosis with calcification was a common disease 8500 years ago; and he holds that it could not have been associated with hard work or alcohol, for the ancient Egyptians did not drink spirits, and they had practically the same hours of work as modern Egyptians, with every seventh day free.

A skiagram of a bone in which there is a chondroma shows a clear rounded area in the position of the tumour, which must be differentiated from similar clear areas due to other kinds of tumour, especially the myeloma; when it has undergone calcification or ossification, it gives a shadow as dark as bone. [Illustration: FIG.

Under other circumstances, the tuberculous tissue that has undergone caseation, or even calcification, is only encapsulated by the new fibrous tissue, like a foreign body.

INJURIES: Contusion; Sprain; Rupture Hernia of muscle Dislocation of tendons Wounds Avulsion of tendon. DISEASES OF MUSCLE AND OF TENDONS: Atrophy; "Muscular rheumatism" Fibrositis; Contracture; Myositis; Calcification and Ossification; Tumours. DISEASES OF TENDON SHEATHS: Teno-synovitis.

The favourite method of treating it as though it were the outcome of modern scepticism, malice, or obduracy, is just as absurd as if thenaturalistswere to treat the convictions of their opponents as the result of incredible narrow-mindedness, priestly deception, senility, or calcification of the brain-cells.

Sometimes the thrombus is mixed a red thrombus being deposited on a white one, it may be in alternate layers. When aseptic, a thrombus may become detached and be carried off in the blood-stream as an embolus; it may become organised; or it may degenerate and undergo calcification.

"Perhaps they should be put out of reach of poverty," later felt he "had caused death of wife and son on account of his expensive living." Autopsy: chronic internal hydrocephalus, cerebral arteriosclerosis. Brain weight 1180 grams. Coronary sclerosis with calcification throughout, aortic and pulmonary valvular calcification hypertrophy of heart. Cystitis.

The tumour is firm and elastic in consistence, but certain portions may be densely hard from calcification or ossification, while other portions may be soft and fluctuating as a result of myxomatous degeneration and liquefaction. These tumours grow slowly and painlessly, and may surround nerves and arteries without injuring them. They may cause a deep hollow in the bone from which they originate.

The autopsy showed little save chronic myocarditis with brown atrophy, calcification of part of thyroid, non-united fracture of neck of left femur, moderate coronary arteriosclerosis. "Acute mania." Death from bilateral phthisis with numerous cavities and bilateral pleuritis.