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Updated: May 21, 2025
These variations occur because of a difference in chemical source and determination of the two instincts. While the ovary, stimulated by the thyroid and the adrenal medulla, is the chief determinant of the sex instinct, to the posterior pituitary must be credited the chief hormone of the maternal instinct.
More minute or large moles emerge in the skin, especially if the individual is of a fair type. If a strenuous effort is not made to give the adrenals an opportunity to recuperate, or if adjustment on the part of the other glands does not occur, this stage of intermittent and remittent adrenal inadequacy gives way in turn to the state of permanent adrenal insufficiency.
A type of pituitocentric has an almost uncontrollable craving for sweets. Alcohol and the endocrines remain to be studied. Light, heat and humidity stand in some special relation to the adrenals. Pigment deposit in the skin as protection against light is controlled by the adrenal cortex. The reaction of the skin blood vessels to heat and humidity is regulated by the adrenal medulla.
The condition is probably the result of excessive adrenal stimulation by the excessive heat and light of the tropical sun, followed by a reaction of exhaustion and failure, with the consequent phenomena of a form of neurasthenia.
Adrenalin, that weapon of a gland tracing its ancestry back to the begetter of the brain itself, for brain and adrenal gland both have evolved from the small nerve ganglia of the invertebrates, would have backed up to the hilt his argument, which he had to elaborate on the indirect grounds of analogy and induction.
Knowing the state of the internal secretion reservoirs enables us to predict the liability to certain of these infections of childhood. Diphtheria has been found to occur most virulently among adrenal poor individuals. Moreover, they are left poorer in adrenal afterwards. It follows that they would be assisted by the feeding of adrenal.
The degree of masculine trend in a woman is a crude measure of adrenal domination, the degree of feminine deviation in a man is roughly proportional to the amount of pituitary influences in his make-up. Whether one or the other sex tendency will dominate depends upon the quantity of sex hormone divergence from the ideal normal.
The pituitary and the adrenal cortex are mutually assistant, alike in their influence upon the tone of the brain and sex cells. So there are combinations of glands to assist or restrain others, or to control a body function, or to determine the domination or abeyance of an instinct.
Professor Cannon's experiments are most interesting as he traces the variations of the flow of adrenal secretion induced by emotion and then retraces the effect of the chemical changes so produced upon bodily and mental states. The secretion of adrenin is greatly increased by pain or excitement. The percentage of blood sugar is also greatly increased by the same causes.
The sequence of events appears to be about as follows: The amount of post-pituitary secretion reaches a certain concentration. This in turn stimulates the thyroid and adrenal medulla. They in turn activate the ovarian cells, which congest the uterine glands and lining membrane. The follicle bursts, the ovum is discharged and wanders, the uterus waits and wonders.
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