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Updated: June 3, 2025


In other words, the minutest tissue in the body is a source of heat in proportion to the activity of its chemical changes. The more active the changes, the greater is the heat produced, and the greater the amount of urea, carbon dioxid, and water eliminated. The waste caused by this oxidation must be made good by a due supply of food to be built up into protoplasmic material.

If stationary electrodes are employed, the current strength should be about 0.1 ampere, which may, after 12 to 15 hours, be increased to 0.2 ampere. The time required for complete deposition is usually from 20 to 24 hours. No urea is added in this case.

The vital part of the tissues, built up from the complex classes of food, is oxidized by means of the oxygen carried by the arterial blood, and broken down into simpler bodies which at last result in urea, carbon dioxid, and water. Wherever there is life, this process of oxidation is going on, but more energetically in some tissues and organs than in others.

Some of the proximate principles of vegetable and animal bodies, such as urea and alantoin, are said to have been produced artificially by the chemist; and in the combination of the simple elements, such as carbon and oxygen, into these proximate principles, it is now acknowledged that there is no violation of the ordinary laws of chemical affinity.

They correspond to the ashes and gases of ordinary combustion and form wastes that must be removed. A number of mineral salts are also to be included with the waste materials. Some of these are formed in the body, while others, like common salt, enter as a part of the food. They are solids, but, like the urea, leave the body dissolved in water.

The sweat is a turbid, saltish fluid with a feeble but characteristic odor due to certain volatile fatty acids. Urea is always present in small quantities, and its proportion may be largely increased when there is deficiency of elimination by the kidneys. Thus it is often observed that the sweat is more abundant when the kidneys are inactive, and the reverse is true.

These waste-stuffs, called urea and urates, are formed in the liver and brought in the blood to the kidneys. These lie on either side of the backbone, opposite the small of the back, their lower ends being level with the highest point of the hip-bones, nearly six inches higher than they are usually supposed to be.

Two large arteries from the aorta, called the renal arteries, supply them with blood, and they are connected with the inferior vena cava by the renal veins. They remove from the blood an exceedingly complex liquid, called the urine, the principal constituents of which are water, salts of different kinds, coloring matter, and urea. The kidneys. 2. Ureters. 3. Bladder. 4. Aorta. 5.

The muscles also have been suggested as a likely source of urea, for here the proteids are broken down in largest quantities; but the muscles produce little if any urea. Its production has been found to be the work of the liver.

Mary Putnam Jacobi in the Boylston prize essay for 1876; showing that menstrual life is associated with a wave of well-marked vital energy, which manifests itself in a monthly fluctuation of the tempera ture of the body, in the daily amount of the excretion of urea and of carbonic acid, and of the rate and tension of the pulse.

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