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Second, the size and disposal of the sinuses, the state of nutrition in childhood have far more to do with the "bumps" of the head than brain or character. The bump of philoprogenitiveness has in my experience more often been the result of rickets than a sign of parental love. It is to be remembered that phrenology had a good standing at one time, though it has since lapsed into quackdom.

Epithelioma frequently originates in long-standing ulcers or sinuses, and in scars, and probably results from the displacement and sequestration of epithelial cells during the process of cicatrisation. The columnar epithelial cancer or columnar epithelioma originates in mucous membranes covered with columnar epithelium, and is chiefly met with in the stomach and intestine.

Less frequently there is more than one collection of pus under the periosteum, each being derived from a focus of suppuration in the subjacent marrow. The pus perforates the periosteum, and makes its way to the surface by the easiest anatomical route, and discharges externally, forming one or more sinuses through which fresh infection may take place.

In man also the clinical features of the chronic variety of the disease are somewhat different from those of the acute form. Here, too, infection takes place through a broken cutaneous surface, and leads to a superficial lymphangitis with nodular thickening of the lymphatics (farcy buds). The neighbouring glands soon become swollen and indurated. The primary lesion meanwhile inflames, suppurates, and, after breaking down, leaves a large, irregular ulcer with thickened edges and a foul, purulent or bloody discharge. The glands break down in the same way, and lead to wide destruction of skin, and the resulting sinuses and ulcers are exceedingly intractable. Secondary deposits in the subcutaneous tissue, the muscles, and other parts, are not uncommon, and the nasal mucous membrane may become involved. The disease often runs a chronic course, extending to four or five months, or even longer. Recovery takes place in about 50

The roof of the mouth, the teeth, the hard gums, the cones of the nasal passage, and the sinuses are the solid portions of the cavities of resonance. When Svengali gazed into Trilby's mouth and exclaimed, "Himmel, what a roof!" he spoke from the depths of vocal knowledge.

Delicate hairs may also be found projecting from the epithelial lining of the cyst. Faulty coalescence of the cutaneous covering of the back occurs most frequently over the lower sacral vertebræ, giving rise to small congenital recesses, known as post-anal dimples and coccygeal sinuses. These recesses are lined with skin, which is furnished with hairs, sebaceous and sweat glands.

Their size and consistence are variable sometimes soft, tearing with the greatest facility, and bleeding at the slightest touch; at other times, solid and covered with pituitary membrane. They are generally the result of ulcerations, wounds, fractures, perforations of the turbinated bones, sinuses,&c.

Feb. 29th, 9:30, A. M., pulse 104, temp. 100. The sacks, or sinuses, have been washed out regularly every day, and dressed with vasaline. This case presents several features of interest.

For its cultivation, a warm-house temperature appears most suitable; it bears a close resemblance to E. texensis. Full-sized plants are ft. in diameter, and have about a dozen ridges with acute sinuses, the ridges being rounded and even. The spines are 1 in. long, bristle-like, and are arranged in clusters of seven or nine, with a cushion of white wool at the base of each cluster.

The milk tubules from the different portions of the gland converge and form larger tubules that finally empty into small sinuses or reservoirs at the base of the teat. Leading from these sinuses are one or several milk ducts that open at the summit of the teat. The testicles are the glandular organs that secrete the spermatozoa, the essential elements of the seminal fluid.