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Updated: May 18, 2025


The book gives an interesting account of Mather's share in that great colonial revolution in medicine the introduction of the custom of inoculation for the small-pox. His friend, Dr. Zabdiel Boylston, of Boston, was the first physician to inaugurate this great step by inoculating his own son a child six years old.

The writer has resided in families where little boys of eight, ten, and twelve years old amused themselves, under the direction of their mother, in planting walnuts, chestnuts, and hazelnuts, for future time; as well as in planting and inoculating young fruit-trees of all descriptions.

Toward the end of the century an inoculating hospital was again opened in that city. Early in the eighteenth century inoculation was extensively practiced by Dr. Adam Thomson of Maryland, who was instrumental in spreading a knowledge of the practice throughout the Middle States. Despite inoculation, as we have already seen, during the eighteenth century the mortality from small-pox increased.

Horses, rabbits, rats, donkeys, monkeys, mice, and dogs heavens, they have tried it on them all, tens of thousands of times and a hundred thousand times ten thousand times, and never a successful inoculation! They have never succeeded in inoculating it on one man from another. Here let me show you." And from his shelves Waiter Merritt Emory began pulling down his authorities.

As soon as prohibition became a certainty, certain astute merchants of the Quaker City devoted themselves to inoculating the public with a taste for these humble fritters, and now they bubble gayly in the windows of Philadelphia's most aristocratic thoroughfare.

But culture was not a weed that grew overnight; it was a leaven that spread slowly and painfully, first inoculating a few who suffered and often died for it, that it might gradually affect the many. The spread of culture implied the recognition of leadership: democratic leadership, but still leadership.

When recently from England came the news of the discovery of vaccination and I saw how a small drop could penetrate through a man's entire system, then I regretted that my father had thrown away the elixir. If I still possessed it I would, despite my advanced age, try the experiment of inoculating myself with it.

When recently from England came the news of the discovery of vaccination and I saw how a small drop could penetrate through a man's entire system, then I regretted that my father had thrown away the elixir. If I still possessed it I would, despite my advanced age, try the experiment of inoculating myself with it.

I wou'd say, if I meant the Verses an Encomium they shou'd be envied for, That their Subject need not blush at them! On Lady Mary Wortley Montagu's bringing with her, out of Turkey, the Art of Inoculating the Small-Pox. When Greece, reviving into short Delight, Felt Pride, and Comfort, at Our Muse's Sight: The Rival'd Nine no sooner saw her Face, But ev'n their Envy gave their Wonder Place!

His opinion respecting the safety of inoculating for the small-pox at a proper age, as it was expressed in the following letter to the writer of these pages, will be satisfactory to such parents as are yet unconvinced of the efficacy of vaccination; and his opinion is the more valuable, because it was given at a time when there was neither prejudice nor prepossession on the subject.

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