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In children under one year of age, the normal average is from 10,000 to 20,000. Absence of Leucocytosis Leucopenia. In certain infective diseases the number of leucocytes in the circulating blood is abnormally low 3000 or 4000 and this condition is known as leucopenia.
The occurrence of endocarditis, as indicated by alterations in the heart sounds and the development of murmurs, may cause widespread infective embolism, and metastatic suppurations in the kidneys, heart-wall, and lungs, as well as in other bones and joints than those primarily affected.
If these measures fail, amputation of the limb may be the only means of preventing further dissemination of infective material from the primary source of infection.
It is, on the whole, more usual and necessary, in order to render it palatable, to apply heat to flesh, fish, and fowl than to fruits. And it is by heat heat of the temperature of boiling water applied for ten minutes or more, that poison-producing and infective bacteria are killed and rendered harmless.
This may be a wound or a purulent blister, and the streptococcus pyogenes is the organism most frequently present. Septic lymphangitis is commonly met with in those who, from the nature of their occupation, handle infective material. A gonococcal form has been observed in those suffering from gonorrhœa.
Delirium is a temporary disturbance of mind which occurs in the course of certain diseases, and sometimes after injuries or operations. It may be associated with any of the acute pyogenic infections; with erysipelas, especially when it affects the head or face; or with chronic infective diseases of the urinary organs.
But there should have been painstaking investigation, even after the fact. There should have been a collection of infective material and a reasonably complete identification and study of the infective agent. It hadn't been made. There was probably some other emergency at the time, and it slipped by.
Where the inflammation becomes infective, surgical interference is necessary. The prompt evacuation of pus, with adequate provision for wound discharge, should be attended to before extensive destruction of tissue takes place. Resolution is prompt as a rule in such cases because of the vascularity of the structures and the ease with which proper drainage may be effected.
Of the bacteria and similar microscopic germs of disease to which all our infective fevers are due we have only become aware quite recently, within the half-century. Before they were known, cleanliness and the destruction of putrescible matter in man's surroundings had, it is true, been urged by sanitary reformers.
These may lodge in distant parts, and give rise to secondary foci of suppuration pyæmic abscesses. Clinical Features. Infective phlebitis is most frequently met with in the transverse sinus as a sequel to chronic suppuration in the mastoid antrum and middle ear.
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