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Updated: May 7, 2025
I should fancy that the above particulars are sufficent to completely differentiate atropine from all the other mydriatic alkaloids. Planta has already tried to show that atropine is identical with the daturine obtained by Geiger and Hesse, founding his opinion on facts which we nowadays look upon as doubtful. This identity was generally admitted by all chemists.
I tried to look wise, but all I could think of was that, whatever his science showed me now, my instinct had been enough to prompt me not to smoke those cigarettes, though, of course, only Kennedy's science could tell what it was that caused that instinctive aversion. "They are all like atropine, mydriatic alkaloids," he proceeded, "so called from the effect they have on the eye.
Sure enough, as I had expected, Kennedy was in his laboratory. As we entered he was verifying his experiments and checking over his results, carefully endeavouring to isolate any of the other closely related mydriatic alkaloids that might be contained in the noxious fumes of the poisoned tobacco.
We translate the following important article, says the Chemists' Journal, from the Moniteur Scientifique of last month. It may be explained for the sake of our student readers that the word mydriatic is derived from the Greek mudriasis, which means paralysis of the pupil.
According to the early researches we could not discover any of these relationships which only become evident when we come to study the new discoveries which have been made in connection with the tropines, to which class belong both duboisine and hyoscyamine, which, although differing from atropine, are equally mydriatic in their action. Discovered by Mein in 1831 in the roots of belladonna.
I met him again the next day and he still was an odd-looking creature indeed, with one eye a light blue and the other an absolute black. The thing puzzled me until I recalled that the Latin name of jimson weed is Datura stramonium; then, in a flash, it came to me that stramonium is a powerful mydriatic.
That is one of the effects of the mydriatic alkaloids, of which this is one. The ancients were familiar with several of its peculiar properties, as they knew of the closely allied poison hemlock. "Many of the text-books at the present time fail to say anything about the remarkable effect produced by large doses of this terrible alkaloid.
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