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Updated: June 12, 2025
Johann Müller, the most celebrated physiologist of his day and contemporary of Henle, wrote in 1844 and coolly stated, "The ductless glands are alike in one particular they either produce a different change in the blood which circulates through them or the lymph which they elaborate plays a special rôle in the formation of blood or of chyle."
It was now for the first time that a true general anatomy became possible. As early as 1816 Treviranus had attempted to resolve the tissues, of which Bichat had admitted no less than twenty-one, into their simple microscopic elements. How could such an attempt succeed, Henle well asks, at a time when the most extensively diffused of all the tissues, the areolar, was not at all understood?
But by the German naturalists Muller and Henle, who, in christening the sharks, have bestowed upon them the most heathenish names, they are classed under one family; which family, according to Muller, king-at-arms, is an undoubted branch of the ancient and famous tribe of the Chondropterygii. To begin.
Ten years earlier Henle had demonstrated the existence of annular bands of muscle fibres in the arterioles, hitherto a much-mooted question, and several tentative explanations of the action of these fibres had been made, particularly by the brothers Weber, by Stilling, who, as early as 1840, had ventured to speak of "vaso-motor" nerves, and by Schiff, who was hard upon the same track at the time of Bernard's discovery.
At the moment when these observations were communicated to him Schwann was puzzling over certain details of animal histology which he could not clearly explain. Then, too, the researches of Friedrich Henle had shown that the particles that make up the epidermis of animals are very cell-like in appearance.
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