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In the cortex and in the cerebellum, the changes in the brain-cells were in every instance more marked than in the medulla. There is also strong NEGATIVE evidence that traumatic impulses are not excluded by ether anesthesia from the part of the brain that is apparently asleep.
In like manner, the brain may be sensitized by the administration of large doses of thyroid extract prior to operation, the threshold to injury in such a case continuing to be low to traumatic stimuli even under anesthesia. Under the sensitizing influences of thyroid extract or of Graves' disease the effect of an injury, of an operation, or of emotional excitation is heightened.
Under light ether anesthesia, severe manipulations of the peritoneum often cause such vigorous contractions of the abdominal muscles that the operator is greatly hindered in his work.
Deep narcosis and anesthesia were induced, and two hours after awakening his breath smelled strongly of iodoform. There are two similar instances recorded in England. Pope mentions two fatal cases of lead-poisoning from diachylon plaster, self-administered for the purpose of producing abortion.
Whether the energy of the brain be discharged by injury under anesthesia or by ordinary muscular exertion, identical morphologic changes are seen in the nerve-cells. It is quite clear that in each of these cases the altered function and form of the brain-cells are due to an *excessive discharge of nervous energy.
In the electric fish a part of the muscular mechanism is replaced by a specialized structure for storing and discharging electricity. We found further that electric fish could not discharge their electricity when under anesthesia, and clinically we know that under deep morphin narcosis, and under anesthesia, the production both of heat and of muscular action is hindered.
These observations lead naturally to the question, May not acidity of itself be the actual final cause of death? In view of these facts may we not find that anesthesia and many instances of unconsciousness are merely phenomena of acidity? As has been stated already, we have found that the H-ion concentration of the blood its acidity is increased by alcohol, by ether, and by nitrous oxid.
So carried and so held, we came into a high inner hall, gray and bare, and were brought before a majestic gray-haired woman who seemed to hold a judicial position. There was some talk, not much, among them, and then suddenly there fell upon each of us at once a firm hand holding a wetted cloth before mouth and nose an order of swimming sweetness anesthesia. A Peculiar Imprisonment
By anesthetizing the same area he could stop immediately severe attacks of asthma and of coughing. Another area in the nasal cavity corresponds to the genital organs. The doctor proved that by electric irritation applied to this area abortions could be produced, and that by anesthesia of the same area in the nose, uterine hemorrhages could be stopped.
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