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Two generations back they still stood dark and empty; people avoided them as they passed by; the boldest schoolboy only shouted through the key-hole and made off; for within, it was supposed, the plague lay ambushed like a basilisk, ready to flow forth and spread blain and pustule through the city. What a terrible next-door neighbour for superstitious citizens!
He was, therefore, inoculated with variolous matter from a fresh pustule; but, as in the preceding cases, the system did not feel the effects of it in the smallest degree. I had an opportunity also of having this boy and William Pead inoculated by my nephew, Mr.
The heat had been trying. He had almost suffered a sunstroke, and twice a mosquito bite had given him much trouble he had feared that he would die of malignant pustule.
Wagner, who has related several cases of malignant pustule produced in man and beasts, both by contact and by eating the flesh of diseased animals, which happened in the village of Striessa in Saxony, in 1834, gives two very remarkable cases which occurred eight days after any beast had been affected with the disease.
My surprise at this sudden transition from extreme sickness to health in great measure ceased when I observed that the inoculated pustule had occasioned, in this case, the common efflorescent appearance around it, and that as it approached the centre it was nearly in an erysipelatous state.
The disease took a variety of forms. There were those who had nothing but the symptoms, or a pustule or two; some had a few dozen on them, scattered from head to foot; they were almost absolutely well; they refused to be made invalids of; they kept at work on the farm or were only disabled for a day or two when the disease was at its height.
At the time when the pustule was destroyed in the arm of Mary James I was informed she had been indisposed about twelve hours; but I am now assured by those who were with her that the space of time was much less.
The ideal means of helping the tissues is by removing the focus of infection, and when this can be done, as for example in a carbuncle or an anthrax pustule, the infected area may be completely excised. When the focus is not sufficiently limited to admit of this, the infected tissue may be scraped away with the sharp spoon, or destroyed by caustics or by the actual cautery.
I do not consider this as, in any degree diminishing the value of this important discovery and practice. Very few practitioners understand this business; and a great number of people in the United States have inoculated themselves, without knowing at what period to take the matter; and without knowing the true pustule from the spurious.
#Clinical Features of Malignant Pustule.# We shall here confine ourselves to the consideration of the local lesion as it occurs in the skin the malignant pustule. The point of infection is usually on an uncovered part of the body, such as the face, hands, arms, or back of the neck, and the wound may be exceedingly minute.
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