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The subject is still hidden in darkness to the extent of insufficient knowledge on our part of the exact constituents of the active agents in the secretions of the testes, thyroids, suprarenals, pituitary and other glands.
This is therefore the kind of organ which would be expected to be affected by hormones from the generative organs. It is stated that the sexual instincts were also unaltered, a male containing ovaries instead of testes readily copulating with a normal female. Univ. Cases in Lepidoptera, e.g. Amphidasys betularia, have frequently been recorded.
Loeb actually supposes that the thyroid is the cause of the development of the legs. Logically, if this were the case it would follow that if we fed an eel or a snake with thyroid it would develop legs like those of a frog, and if a man were injected with extract of the testes of a stag he would develop antlers on his forehead.
Will an intense and continuous desire on the part of a young man for sexual intercourse cause a loss of seminal fluid? An intense and continuous desire for sexual intercourse will, without question, cause an active secretion on the part of the testes, an increased secretion on the part of the seminal vesicles and an active secretion on the part of the prostate gland and of Cowper's glands.
The spleen, liver, testes, and mammæ may be enlarged; the glandular swellings press on important structures, such as the trachea, œsophagus, or great veins, and symptoms referable to such pressure manifest themselves. Diagnosis. Considerable difficulty attends the diagnosis of lymphadenoma at an early stage.
The facts concerning cryptorchidism, that is to say, failure of the descent of the testes in Mammals, seem to show that the hormone of the testis is not derived from semen or spermatogenesis, for in the testes which have remained in the abdomen there is no spermatogenesis, while the interstitial cells are present, and the animals in some cases exhibit normal or even excessive sexual instinct, and all the male characteristics are well marked.
It is shown, therefore, that the loss of the nuptial plumage takes place in June when spermatogenesis has ceased and the testes are diminishing in size, but the redevelopment of this plumage takes place in September without any renewed activity of the testis and long before the beginning of spermatogenesis. The case of the antlers in the stag is probably very similar.
In some cases, where the activity of the gonads is limited to a particular season of the year, the sexual characters or organs are developed at this season, and then disappear again, so that there is a periodic development corresponding to the periodic activity of the testes or ovaries.
The external secretion of the testes is that which is poured out in a sexual emission, as described above; the internal secretion of the testes consists of substances formed by the testes of sexually mature individuals, which substances, poured into the blood, profoundly affect the development of the individual and his whole physical and psychical character.
Among the names of the fourteenth century are those of Gautier de Bruceles, Renier de Treit, Gautier de Poulogne, and Jean de Laon, while Jean Harent of Calais is recorded as having worked, for Mme. d'Artois, in 1319, a robe decorated "a bestelettes et a testes."
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