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Lympho-sarcoma can usually be differentiated by the rapid assumption of the local features of malignant disease, and in a gland removed for examination, a predominance of small round cells with scanty protoplasm. The enlargement associated with leucocythæmia is differentiated by the characteristic changes in the blood. Treatment. In the acute form of lymphadenoma, treatment is of little avail.

#Leucocythæmia.# This is a disease of the blood and of the blood-forming organs, in which there is a great increase in the number, and an alteration of the character, of the leucocytes present in the blood. It may simulate lymphadenoma, because, in certain forms of the disease, the lymph glands, especially those in the neck, axilla, and groin, are greatly enlarged.

Anatomy and Physiology INJURIES OF LYMPH VESSELS Wounds of thoracic duct DISEASES OF LYMPH VESSELS Lymphangitis: Varieties Lymphangiectasis Filarial disease Lymphangioma DISEASES OF LYMPH GLANDS Lymphadenitis: Septic; Tuberculous; Syphilitic Lymphadenoma Leucocythæmia TUMOURS. #Surgical Anatomy and Physiology.# Lymph is essentially blood plasma, which has passed through the walls of capillaries.

The chief importance lies in differentiating tuberculous disease from lympho-sarcoma and from lymphadenoma, and this is usually possible from the history and from the nature of the enlargement. Signs of liquefaction and suppuration support the diagnosis of tubercle. If any doubt remains, one of the glands should be removed and submitted to microscopical examination.

The spleen, liver, testes, and mammæ may be enlarged; the glandular swellings press on important structures, such as the trachea, œsophagus, or great veins, and symptoms referable to such pressure manifest themselves. Diagnosis. Considerable difficulty attends the diagnosis of lymphadenoma at an early stage.