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Updated: June 24, 2025


Systemic Treatment. As this complication most frequently occurs during acute rheumatism, the question arises as to the value or harmfulness of salicylates and alkaline drugs. While salicylic acid will not prevent endocarditis, it should he continued, if it is of benefit with regard to the arthritis. The indication for its use depends on its effect on the joints.

After this has been secured, the usual plan is to assist nature in the elimination of the toxins by alkalies, alkaline mineral waters, and other laxatives; to relieve the pain, promote the comfort, and improve the rest of the patient by a variety of harmless nerve-deadeners or pain-relievers, chief among which are the salicylates, aspirin, and the milder coal-tar products.

The chief points in the differential diagnosis from acute articular rheumatism are, that the gonorrhœal affection is more often confined to one or two joints, has little tendency to wander from joint to joint, and its progress is not appreciably influenced by salicylates, although these drugs may relieve pain.

When the inflammation occurs as a complication of acute rheumatism, it has been suggested that salicylates, which arc not inhibiting rheumatism and may be depressant to the heart, should be stopped if they are being administered; but if the salicylates are apparently improving the inflammation in the joints, pericarditis would not contraindicate their continued use.

In acute rheumatism, however, the joint symptoms predominate, there is an absence of suppuration, and the pains and temperature yield to salicylates. The prognosis varies with the type of the disease, with its location the vertebræ, skull, pelvis, and lower jaw being specially unfavourable with the multiplicity of the lesions, and with the development of endocarditis and internal metastases.

Isolation, best perhaps away from home, as might be expected, gives the best results. If there are pronounced rheumatic symptoms, the salicylates will be needed; if there is anæmia, arsenic and iron; if there is sleeplessness and great restlessness, bromides or chloral.

After repeated recurrences, there is ankylosis with deformity, the patient becoming a helpless cripple. On account of the tendency to visceral complications, the tenure of life is uncertain. From the nature of the disease, treatment is for the most part palliative. Salicylates are only of service during the exacerbations attended with pyrexia.

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