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Updated: May 14, 2025
In poisoning by lead and copper the accumulation of the poison in the fetal tissues is greater than in the maternal, perhaps from differences in assimilation and disassimilation or from greater diffusion. Whilst it is not an impermeable barrier to the passage of poisons, the placenta offers a varying degree of obstruction: it allows copper and lead to pass easily, arsenic with greater difficulty.
Thus you see I was carrying out the theory mentioned in the first part of this paper: that of supplying the system with all the flesh producing food the stomach would digest, and using whisky and quinia to prevent disassimilation or waste; also vasaline locally for a similar reason.
Asphyxia would surely end the matter! And why? The excessive exercise of the whole body is setting free from the tissues such an amount of excretive matter, and carbon more largely than all the others, that, without a relative action of the lungs to admit the air that oxygen may be absorbed, carbonic acid gas cannot be liberated through the lungs as fast as the waste carbon of the overworked tissues is being made by disassimilation from this excess of respiration.
For the obese from default of disassimilation, Robin recommends a regimen of green vegetables and bread chiefly the latter in small quantities, however, and fluids as may be desired.
Professor Schäfer, in his presidential address before the British Association in 1912, argued that all the main characteristics of living matter, such as assimilation and disassimilation, growth and reproduction, spontaneous and amoeboid movement, osmotic pressure, karyokinesis, etc., were equally apparent in the non-living; therefore he concluded that life is only one of the many chemical reactions, and that it is not improbable that it will yet be produced by chemical synthesis in the laboratory.
Augmentation of assimilation. 2. Reduced disassimilation. In the former, he insists water must be interdicted, while in the latter it may be allowed ad libitum. Again, in order to recognize the exact variety of obesity, he divides his patients into three classes, each recognizable by the volume of urea excreted.
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