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The conditions likely to be mistaken for surgical actinomycosis are sarcoma, tubercle, and syphilis. In the early stages the differential diagnosis is exceedingly difficult. In many cases it is only possible when suppuration has occurred and the fungus can be demonstrated.

The general condition of the patient must be improved by tonics, good food, and favourable hygienic surroundings. In some cases potassium iodide acts beneficially. Actinomycosis is a chronic disease due to the action of an organism somewhat higher in the vegetable scale than ordinary bacteria the streptothrix actinomyces or ray fungus.

Actinomycosis of the lungs sometimes occurs. Swine and horses may be affected by this disease. This fungus grows on certain plants, and the animal usually contracts the disease by eating plants or roughage that have the fungus on them. Grasses having awns that are capable of wounding the mucous membrane of the mouth and penetrating the gums are most apt to produce the disease.

Actinomycosis of the lungs may present the appearance of a chronic pulmonary affection. If the disease involves the head and lungs, the animal may become unthrifty and emaciated. In doubtful cases a microscopic examination of a piece of the tumor, or some of the pus, may be necessary. The treatment is surgical and medicinal. Small, external tumors may be removed by an operation.

When it affects the lower jaw, in its early stages, actinomycosis may closely simulate a periosteal sarcoma. [Illustration: FIG.

If the disease is localised, it may be removed by the knife or sharp spoon, and the part afterwards cauterised. As a rule, amputation well above the disease is the best line of treatment. Unlike actinomycosis, this disease does not appear to be benefited by iodides. [Illustration: FIG.

I greatly fear that actinomycosis is destined to play an important part in the final extinction that seems to be the impending fate of the beautiful and valuable prong-horned antelope. All persons who live in country still inhabited by antelope are urged to watch for this disease. If any antelopes are found dead, see if the lower jaw is badly swollen and discharging pus.

LUMPY-JAW IN ANTELOPE AND SHEEP. It is a lamentable fact that some, at least, of the United States herds of prong-horned antelope are afflicted with a very deadly chronic infective disease known as actinomycosis, or lumpy-jaw. It has been brought into the Zoological Park five times, by specimens shipped from Colorado, Texas, Wyoming and Montana. I think our first cases came to us in 1902.

The black sheep of the Stickine and Iskoot regions are so seldom seen by white men, save when a sportsman kills his allotment of three specimens, we really do not know anything about the extent to which actinomycosis prevails in those herds, or how deadly are its effects.