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Updated: June 15, 2025
His method of transplanting the glands into a man is by making two incisions in the man's scrotum under simple local anesthesia, a practically painless operation, but from this point on the technique varies according to the conditions presented by the case. No two cases are exactly alike, and Dr. Brinkley performs no two operations exactly alike.
It has long been known that the vasomotor, the cardiac, and the respiratory centers discharge energy in response to traumatic stimuli applied to various sensitive regions of the body during surgical anesthesia.
If the acidity is slight, then the anesthesia is slight and the force of the nerve impulses is lessened, but the patient is still conscious of them. As the acidity increases associative memory is lost, and the patient is said to be unconscious: the centers governing the voluntary muscles are not inhibited, however, and cutting the skin causes movements.
His next sensation was that of pain in his lungs. Something that smarted intolerably was being forced into his nostrils, and he battled against the agony it produced. And then he heard someone chuckle amusedly and felt the curious furry sensation of electric anesthesia beginning....
And there were books upon the organization of armies, and upon the chemistry of precious stones. A cursory examination of his books would have found the master of the house to be interested also in obstetrics, in poisons, and in anesthesia; but of romance, humanity, or poetry his library had but a single example, the "Monte Cristo" of the elder Dumas.
Among the unconscious responses to trauma under ether anesthesia are purposeless moving, the withdrawal of the injured part, and, if the anesthesia be sufficiently light and the trauma sufficiently strong, there may be an effort toward escape from the injury.
Just what is the distribution of the receptors for heat and for cold I am unable to state, but this much we do know, that without anesthesia the intestines may be cauterized freely without the least pain resulting, and in animals the cauterization of the brain causes no demonstrable change in the circulatory or respiratory reactions.
The hypodermic administration of epinephrin solutions, 1:10,000, or solutions of pituitary extract, 1:10,000, should be considered; they are often valuable. If the shock occurs in ether or chloroform anesthesia, the vasopressor stimulating effect of inhalations of carbon dioxid gas may be considered, as advised by Henderson."
Neuroses of the skin consist in augmentation of sensibility or hyperesthesia and diminution of sensibility or anesthesia. There are some curious old cases of loss of sensation. Ferdinandus mentions a case of a young man of twenty-four who, after having been seized with insensibility of the whole body with the exception of the head, was cured by purgatives and other remedies.
As William James, with his unerring discernment, wrote twenty-five years ago: "The reason for craving alcohol is that it is an unaesthetic, even in moderate quantities. Dull lives are vivified by it, a fleeting anesthesia of unhappy memories and longings is effected, and for the moment life seems worth living.
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