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Updated: May 3, 2025
The opsonins, for example, those substances which butter the bacteria so that the appetite of the white cells for them is properly roused, are mobilized by thyroid feeding or injection. Other substances in the blood which destroy and dissolve bacteria are also increased.
These are known as opsonins or alexins, and they act on the bacteria by a process comparable to narcotisation, and render them an easy prey for the phagocytes. Artificial or Passive Immunity. A form of immunity can be induced by the introduction of protective substances obtained from an animal which has been actively immunised. The most important of these antibodies are the antitoxins.
It has still to develop principles that are comparable to the doctrine of lymph therapy or to that latest triumph of investigation in the field of medicine, the theory of opsonins, which almost makes one believe that in a few years violent accident and old age will be the only sources of death in the human race.
The protective effects of the inflammatory reaction depend for the most part upon the transudation of lymph and the emigration of leucocytes. The lymph contains the opsonins which act on the bacteria and render them less able to resist the attack of the phagocytes, as well as the various protective antibodies which neutralise the toxins.
It was opposed simply because doctors and apothecaries lived by selling bottles and boxes of doctor's stuff to be taken in spoonfuls or in pellets as large as peas; and people would not pay as much for drops and globules no bigger than pins' heads. At which point the theory of opsonins comes very opportunely to shake hands with it.
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