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By this important differentiation of the plasson into nucleus and cell-body, the organised cell was evolved from the structureless cytode, the nucleated from the unnucleated plastid. That the first cells to appear on the earth were formed from the Monera by such a differentiation seems to us the only possible view in the present condition of science.

These fibroblasts are large irregular nucleated cells derived mainly from the proliferation of the fixed connective-tissue cells of the part, and to a less extent from the lymphocytes and other mononuclear cells which have migrated from the vessels.

Careful examination further proves that the whole substance of the nettle is made up of a repetition of such masses of nucleated protoplasm, each contained in a wooden case, which is modified in form, sometimes into a woody fibre, sometimes into a duct or spiral vessel, sometimes into a pollen grain, or an ovule.

Now, while there are found in the lowest realm of animal life, organisms like the amoeba of stagnant pools, consisting of nothing more than minute masses of protoplasm, there are others like them which possess a small central body called a nucleus. This is known as nucleated protoplasm. A, nucleus; B, nucleolus; C, protoplasm. Cells.

Cells, again, preside over the chemical processes which elaborate the living fluids; they change their form to become the agents of voluntary and involuntary motion; the soul itself sits on a throne of nucleated cells, and flashes its mandates through skeins of glassy filaments which once were simple chains of vesicles.

The nucleated cells found connected with the cancellated structure of the bones, which I first pointed out and had figured in 1847, and have shown yearly from that time to the present, and the fossa masseterica, a shallow concavity on the ramus of the lower jaw, for the lodgment of the masseter muscle, which acquires significance when examined by the side of the deep cavity on the corresponding part in some carnivora to which it answers, may perhaps be claimed as deserving attention.

Nay, more; in the earliest condition of the human organism, in that state in which it has but just become distinguishable from the egg in which it arises, it is nothing but an aggregation of such corpuscles, and every organ of the body was, once, no more than such an aggregation. Thus a nucleated mass of protoplasm turns out to be what may be termed the structural unit of the human body.

Nay, more: in the earliest condition of the human organism, in that state in which it has but just become distinguishable from the egg in which it arises, it is nothing but an aggregation of such corpuscles, and every organ of the body was, once, no more than such an aggregation. Thus a nucleated mass of protoplasm turns out to be what may be termed the structural unit of the human body.

Careful examination further proves that the whole substance of the nettle is made up of a repetition of such masses of nucleated protoplasm, each contained in a wooden case, which is modified in form, sometimes into a woody fibre, sometimes into a duct or spiral vessel, sometimes into a pollen grain, or an ovule.

Nay, more; in the earliest condition of the human organism, in that state in which it has but just become distinguishable from the egg in which it arises, it is nothing but an aggregation of such corpuscles, and every organ of the body was, once, no more than such an aggregation. Thus a nucleated mass of protoplasm turns out to be what may be termed the structural unit of the human body.