Vietnam or Thailand ? Vote for the TOP Country of the Week !
Updated: June 12, 2025
In this important paper, Porak, after giving some historical notes, describes a long series of experiments performed on the guinea-pig in order to investigate the passage of arsenic, copper, lead, mercury, phosphorus, alizarin, atropin, and eserin through the placenta.
There is a good deal of clinical evidence to indicate that in this type of glaucoma, as well as in the so-called sub-acute varieties, myotic activity is increased by a mixture of pilocarpin and eserin in the same solution, exactly as a mixture of arecalin and eserin is more potent than either of the drugs in separate solution.
The action of the former does not continue longer than an hour after administration and of the latter not more than eight hours. The action of either is mild after the first few minutes. I do not think that anyone has recommended either arecolin or eserin where there is severe purgation.
With arecalin, the alkaloid of the Betel nut, I have no experience, nor have I used its mixture with eserin, recommended by Merck as more potent than either of the drugs in separate solution.
D.M. Campbell in a discussion of laminitis has the following to say regarding the treatment of such cases: Because superpurgation may be followed by laminitis, the advisability of using the active hypodermic cathartics is questioned. Neither arecolin nor eserin can cause superpurgation.
This rule should guide us, namely, to begin with a comparatively weak solution of the selected drug, for example, as Posey has advocated a tenth of a grain of salicylate of eserin to the ounce, and the strength gradually increased so that at the end of some months the patient is using a solution 1 grain to the ounce; or if the pilocarpin is preferred, solutions in double these strengths.
Word Of The Day
Others Looking