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Updated: May 14, 2025


There are compensations resulting when because of insufficiency of a gland, others will endeavour, by manufacturing more of their own secretion, to compensate for the loss. There are mutual co-operations, partnerships, when a gland will oversecrete to assist another, or in response to another which is also oversecreting.

It is when a gland, either in the course of development, or because of the influence of starvation, shock, injury, poisoning or infection, begins to undersecrete or oversecrete that its effects upon growth and nutrition become grossly manifest. A veritable transfiguration of the individual may occur, the black magic of which may perplex him for a lifetime.

The adrenals are organs for the mobilization of energy, physical and mental, for emergencies. They are the glands which meet shocks and neutralize the effects of shock. In the solitary animal, the everyday producers of shock are pain, fright and wounds. The adrenal mechanisms oversecrete to encounter the enemy, and then there is a period of rest and recuperation.

So he may find it necessary to purchase an entirely different size of hat, more commodious clothes, and newly fitting gloves and shoes. At the same time, his family, relatives and friends, discover that the erstwhile generous, frank, neat and punctual and liked, has become stingy and suspicious and slovenly and hated. And all because a gland has begun to undersecrete or to oversecrete.

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