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His chief retainers were the two Uesugi families distinguished as Ogigayatsu Uesugi and Yamanouchi Uesugi, after the names of the palaces where their mansions were situated both of whom held the office of kwanryo hereditarily.

But, in 1518, he was recalled to his province by an attack from the shugo of Izumo, and by financial embarrassment resulting from his own generosity in supplying funds to the Crown and the shogun. Hosokawa Takakuni now became kwanryo, exercising his authority with a high hand.

Generally the Ii, the Hotta, or the Sakai family supplied candidates for the office. The roju or senior ministers called also toshiyori discharged the administration. They resembled the kwanryo of the Muromachi Government.

Though it had been against him chiefly that Mochiuji raged, and though his death was certain had he fallen under the power of the Kamakura kwanryo, Mochiuji's fate caused him such remorse that he attempted to commit suicide and finally became a priest. Thenceforth, the title of governor-general of the Kwanto passed to the Uesugi, two of whom were appointed to act simultaneously.

But not all had the title of kwanryo or wielded the extensive power attached to that office. Only the first four were thus fortunate. From the days of the fifth, Shigeuji, evil times overtook the family. These things fell out in 1439, when Mochiuji died. To avoid confusion it is necessary to note that the chief official in the shogun's court at Muromachi in Kyoto was also called kwanryo.

Muromachi made a futile attempt to levy contributions from the daimyo, and the kwanryo, Hosokawa Masamoto, is recorded to have brusquely said, in effect, that the country could be administered without crowning any sovereign.

Yet once more the untiring Takakuni, aided by Miyoshi Norinaga, Motonaga's son, called also Chokei, drives Yoshiharu and Harumoto from the metropolis, and presently a reconciliation is effected by the good offices of Rokkaku Sadayori, the real power of the kwanryo being thenceforth exercised by the Miyoshi family. Japanese historians have well called it an age of anarchy.

The young shogun, however, did not long survive the punishment of his father's murderers. He died in 1443, at the age of ten, and was succeeded by his brother Yoshimasa, then in his eighth year. During the latter's minority, the administration fell into the hands of Hatakeyama Mochikuni and Hosokawa Katsumoto, who held the office of Muromachi kwanryo alternately.

In 1474, Yoshimasa retired from office and, at the close of the year, his nine-year-old son, Yoshihisa, succeeded him as shogun, the kwanryo being that Hatakeyama Yoshinari whose appearance in the field practically terminated the Onin War.

In short, these three families became the bulwarks of the Ashikaga. An important episode of the Ouchi struggle was that Mitsukane, the third Kamakura kwanryo of the Ashikaga line, moved an army into Musashi to render indirect assistance to the Ouchi cause.