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March 6, 1504, a chamberlain of Cardinal S. Angelo, who had been poisoned, was condemned to death, and in a loud voice he proclaimed that he had committed the murder on the explicit command of Alexander and Cæsar. Cardinals Romolini and Ludovico Borgia at once fled to Naples. Don Micheletto, the man who executed Cæsar's bloody orders, was a prisoner in the castle of S. Angelo.

We do not know how the unfortunate Rodrigo spent the first years following Alexander's death and Cæsar's exile in Spain, but there is ground for believing that he was left in Naples under the guardianship of the cardinals Ludovico Borgia and Romolini of Sorrento.

Its university attracted a great many of the sons of the prominent Italian families, chiefly on account of the fame of its professor of jurisprudence, Philippo Decio of Milan. At the university the young Borgia had two Spanish companions, who were favorites of his father, Francesco Romolini of Ilerda and Juan Vera of Arcilla in the kingdom of Valencia.

He recommended his trusted familiar, Francesco Romolini, to Piero for appointment as professor of canon law in Pisa. The letter is signed, "Your brother, Cesar de Borja, Elector of Valencia." By not allowing his son to come to Rome immediately, Alexander wished to give public proof of what he had declared at the time of his election; namely, that he would hold himself above all nepotism.

The latter was master of his household, as Cæsar himself states in a letter written in October, 1492, in which he also calls Romolini his "most faithful comrade." Francesco Romolini was more than thirty years of age in 1491. He was a diligent student of law, and became deeply learned in it. He is the same Romolini who afterwards conducted the prosecution of Savonarola in Florence.