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Updated: May 19, 2025
"I can dig through a whole library of horse practice, and muddle and mull over the Mendelian Law until I'm dizzy, like the clod that I am; but she is the genius. She doesn't have to study law. She just knows it in some witch-like, intuitional way.
When you are carrying out Mendelian experiments on peas, you can enclose your flowers in muslin bags and prevent anything interfering with your observations. And in the stud-farm you can keep the occupants shut up. But what are you going to do with Jack? and with Jill? And still more with Joan? They cannot be permanently isolated, neither are they restrained by any "mythical ideas of sin."
But that every distinct hereditary character of man was actually present as a Mendelian factor in the ancestral Amoeba, and that man is merely a group of the whole complex of characters allowed to produce real effects by the removal of a host of inhibiting factors, is incredible.
The Mendelian hypothesis which explains these results is that the male is always heterozygous, or has only one colour factor whether yellow or black, and transmits these colours only to his daughters, while the female has two colour factors, either BB, YY, or BY. Thus the crosses are: YELLOW male x BLACK female YO male BB female | \/ | | /\ | YB female BO male Tortoise-shell female BLACK male
A beginning of this study of endocrine inheritance, on the pathologic side, has been made. Some of these have been along Mendelian lines. If an endocrine abnormality like a goitre, or cretinism, or a dwarf or giant appear in a family as a sign of endocrine instability, other members of that family will very likely show internal secretion abnormalities.
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