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Updated: May 18, 2025
In some cases benefit has followed the prolonged internal administration of liquid paraffin. On the assumption that the condition is the result of an auto-intoxication from the intestinal tract, saline purges and irrigation of the colon are indicated, and Arbuthnot Lane claims to have brought about improvement by short-circuiting or by resecting the colon.
If food be thoroughly masticated much that would otherwise be hard to digest can be eaten without bad results. One of the best known examples of this is meat, which, while full of nourishment, sets up in the large intestine a condition known as "auto-intoxication," a species of digestive poison. If meat be eaten slowly and chewed thoroughly, this condition is almost entirely absent.
Ptomaine poisoning, as every one knows, results when we eat food that has begun to decay. "Ptomaines are chemical compounds of an alkaloidal nature formed in protein substances during putrefaction. They are purely chemical bodies and differ from the toxins. There are also what are called leucomaines, formed in living tissues, and when not given off by the body they produce auto-intoxication.
By many writers it is believed to depend upon some form of auto-intoxication, the toxins being absorbed from the gastro-intestinal tract, and those who suffer are supposed to possess what has been called an "arthritic diathesis." The localisation of the disease in a particular joint may be determined by several factors, of which trauma appears to be the most important.
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