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In the majority of instances, when there is occasioned serious inconvenience, the outcome is not likely to be favorable, according to Möller. Detachment of a portion of the thrombus, according to Hoare, may result in the lodgment of an embolus in the brain or kidneys. The latter authority also states that muscular atrophy may occur owing to lack of blood supply in some of these cases.

There is sudden pain at the site of impaction of the embolus, and the pulses beyond are lost. The limb becomes cold, numb, insensitive, and powerless. It is often pale at first hence the term "white gangrene" sometimes applicable to the early appearances, which closely resemble those presented by the limb of a corpse.

#Embolism.# The term embolus is applied to any body carried along in the circulation and ultimately becoming impacted in a blood vessel. This occurrence is known as embolism. The commonest forms of embolus are portions of thrombi or of fibrinous formations on the valves of the heart, the latter being usually infected with micro-organisms.

A portion of the fibrin-like lining of the aneurism may flake off and drift along in the blood stream, until finally a vessel that is too small for the floating particle or embolus to pass through is reached. The vessel is then plugged or a thrombus is formed.

"Is there any change?" Louis asked. Rachel shook her head "No," she said. "We just have to sit and watch." "Doctor's coming in again to-night, isn't he?" Rachel nodded. "It seems it's an embolus." Rachel nodded once more. She had still no conception of what an embolus was; but she naturally assumed that Louis could define an embolus with exactitude.